<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:dt="uuid:C2F41010-65B3-11d1-A29F-00AA00C14882" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40"> <head> <meta http-equiv=Content-Type content="text/html; charset=unicode"> <meta name=ProgId content=Word.Document> <meta name=Generator content="Microsoft Word 15"> <meta name=Originator content="Microsoft Word 15"> <link rel=File-List href="listo.fld/filelist.xml"> <link rel=Edit-Time-Data href="listo.fld/editdata.mso"> <!--[if !mso]> <style> v\:* {behavior:url(#default#VML);} o\:* {behavior:url(#default#VML);} w\:* {behavior:url(#default#VML);} .shape {behavior:url(#default#VML);} </style> <![endif]--> <title>CAMPAA NACIONAL  PRIMERO ECUADOR LOGR SUS OBJETIVOS?</title> <!--[if gte mso 9]><xml> <o:DocumentProperties> <o:Author>POR: Lcda. Diana Frez</o:Author> <o:LastAuthor>Microsoft Office User</o:LastAuthor> <o:Revision>3</o:Revision> <o:TotalTime>5</o:TotalTime> <o:LastPrinted>2019-07-25T01:54:00Z</o:LastPrinted> <o:Created>2019-07-25T01:54:00Z</o:Created> <o:LastSaved>2019-07-25T17:01:00Z</o:LastSaved> <o:Pages>10</o:Pages> <o:Words>3560</o:Words> <o:Characters>19583</o:Characters> <o:Company>Maestra en Diseo y Gestin de Marcas</o:Company> <o:Lines>163</o:Lines> <o:Paragraphs>46</o:Paragraphs> <o:CharactersWithSpaces>23097</o:CharactersWithSpaces> <o:Version>16.00</o:Version> </o:DocumentProperties> <o:CustomDocumentProperties> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_0_1 dt:dt="string">http://www.zotero.org/styles/american-medical-association</o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_0_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_0_1 dt:dt="string">American Medical Association</o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_0_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_1_1 dt:dt="string">http://www.zotero.org/styles/american-political-science-association</o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_1_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_1_1 dt:dt="string">American Political Science Association</o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_1_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_2_1 dt:dt="string">http://www.zotero.org/styles/apa</o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_2_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_2_1 dt:dt="string">American Psychological Association 6th edition</o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_2_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_3_1 dt:dt="string">http://www.zotero.org/styles/american-sociological-association</o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_3_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_3_1 dt:dt="string">American Sociological Association</o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_3_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_4_1 dt:dt="string">http://www.zotero.org/styles/chicago-author-date</o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_4_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_4_1 dt:dt="string">Chicago Manual of Style 17th edition (author-date)</o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_4_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_5_1 dt:dt="string">http://www.zotero.org/styles/harvard-cite-them-right</o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_5_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_5_1 dt:dt="string">Cite Them Right 10th edition - Harvard</o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_5_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_6_1 dt:dt="string">http://www.zotero.org/styles/ieee</o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_6_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_6_1 dt:dt="string">IEEE</o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_6_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_7_1 dt:dt="string">http://www.zotero.org/styles/modern-humanities-research-association</o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_7_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_7_1 dt:dt="string">Modern Humanities Research Association 3rd edition (note with bibliography)</o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_7_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_8_1 dt:dt="string">http://www.zotero.org/styles/modern-language-association</o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_8_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_8_1 dt:dt="string">Modern Language Association 8th edition</o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_8_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_9_1 dt:dt="string">http://www.zotero.org/styles/nature</o:Mendeley_x0020_Recent_x0020_Style_x0020_Id_x0020_9_1> <o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_9_1 dt:dt="string">Nature</o:Mendeley_x0020_Recent_x0020_Style_x0020_Name_x0020_9_1> <o:Mendeley_x0020_Document_1 dt:dt="string">True</o:Mendeley_x0020_Document_1> <o:Mendeley_x0020_Unique_x0020_User_x0020_Id_1 dt:dt="string">9cf0be0f-0f90-3b5a-895c-c20f7e102ebd</o:Mendeley_x0020_Unique_x0020_User_x0020_Id_1> <o:Mendeley_x0020_Citation_x0020_Style_1 dt:dt="string">http://www.zotero.org/styles/apa</o:Mendeley_x0020_Citation_x0020_Style_1> </o:CustomDocumentProperties> <o:OfficeDocumentSettings> <o:AllowPNG/> </o:OfficeDocumentSettings> </xml><![endif]--> <link rel=dataStoreItem href="listo.fld/item0009.xml" target="listo.fld/props010.xml"> <link rel=themeData href="listo.fld/themedata.thmx"> <link rel=colorSchemeMapping href="listo.fld/colorschememapping.xml"> <!--[if gte mso 9]><xml> <w:WordDocument> <w:View>Print</w:View> <w:Zoom>123</w:Zoom> <w:SpellingState>Clean</w:SpellingState> <w:GrammarState>Clean</w:GrammarState> <w:TrackMoves>false</w:TrackMoves> <w:TrackFormatting/> <w:HyphenationZone>21</w:HyphenationZone> <w:PunctuationKerning/> <w:DrawingGridHorizontalSpacing>5,5 pto</w:DrawingGridHorizontalSpacing> <w:DisplayHorizontalDrawingGridEvery>2</w:DisplayHorizontalDrawingGridEvery> <w:DisplayVerticalDrawingGridEvery>2</w:DisplayVerticalDrawingGridEvery> <w:ValidateAgainstSchemas/> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF/> <w:LidThemeOther>ES</w:LidThemeOther> <w:LidThemeAsian>JA</w:LidThemeAsian> <w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables/> <w:SnapToGridInCell/> <w:WrapTextWithPunct/> <w:UseAsianBreakRules/> <w:DontGrowAutofit/> <w:SplitPgBreakAndParaMark/> <w:EnableOpenTypeKerning/> <w:DontFlipMirrorIndents/> <w:OverrideTableStyleHps/> </w:Compatibility> <w:BrowserLevel>MicrosoftInternetExplorer4</w:BrowserLevel> <m:mathPr> <m:mathFont m:val="Cambria Math"/> <m:brkBin m:val="before"/> <m:brkBinSub m:val="&#45;-"/> <m:smallFrac m:val="off"/> <m:dispDef/> <m:lMargin m:val="0"/> <m:rMargin m:val="0"/> <m:defJc m:val="centerGroup"/> <m:wrapIndent m:val="1440"/> <m:intLim m:val="subSup"/> <m:naryLim m:val="undOvr"/> </m:mathPr></w:WordDocument> </xml><![endif]--><!--[if gte mso 9]><xml> <w:LatentStyles DefLockedState="false" DefUnhideWhenUsed="false" DefSemiHidden="false" DefQFormat="false" DefPriority="99" LatentStyleCount="376"> <w:LsdException Locked="false" Priority="0" QFormat="true" Name="Normal"/> <w:LsdException Locked="false" Priority="9" QFormat="true" Name="heading 1"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 2"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 3"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 4"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 5"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 6"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 7"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 8"/> <w:LsdException Locked="false" Priority="9" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="heading 9"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 5"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 6"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 7"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 8"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index 9"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 1"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 2"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 3"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 4"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 5"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 6"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 7"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 8"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" Name="toc 9"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Normal Indent"/> <w:LsdException Locked="false" Priority="0" SemiHidden="true" UnhideWhenUsed="true" Name="footnote text"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="annotation text"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="header"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="footer"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="index heading"/> <w:LsdException Locked="false" Priority="35" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="caption"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="table of figures"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="envelope address"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="envelope return"/> <w:LsdException Locked="false" Priority="0" SemiHidden="true" UnhideWhenUsed="true" Name="footnote reference"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="annotation reference"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="line number"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="page number"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="endnote reference"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="endnote text"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="table of authorities"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="macro"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="toa heading"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Bullet"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Number"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List 5"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Bullet 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Bullet 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Bullet 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Bullet 5"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Number 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Number 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Number 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Number 5"/> <w:LsdException Locked="false" Priority="10" QFormat="true" Name="Title"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Closing"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Signature"/> <w:LsdException Locked="false" Priority="1" SemiHidden="true" UnhideWhenUsed="true" Name="Default Paragraph Font"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text Indent"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Continue"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Continue 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Continue 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Continue 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="List Continue 5"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Message Header"/> <w:LsdException Locked="false" Priority="11" QFormat="true" Name="Subtitle"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Salutation"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Date"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text First Indent"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text First Indent 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Note Heading"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text Indent 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Body Text Indent 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Block Text"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Hyperlink"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="FollowedHyperlink"/> <w:LsdException Locked="false" Priority="22" QFormat="true" Name="Strong"/> <w:LsdException Locked="false" Priority="20" QFormat="true" Name="Emphasis"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Document Map"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Plain Text"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="E-mail Signature"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Top of Form"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Bottom of Form"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Normal (Web)"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Acronym"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Address"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Cite"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Code"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Definition"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Keyboard"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Preformatted"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Sample"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Typewriter"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="HTML Variable"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Normal Table"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="annotation subject"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="No List"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Outline List 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Outline List 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Outline List 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Simple 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Simple 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Simple 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Classic 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Classic 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Classic 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Classic 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Colorful 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Colorful 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Colorful 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Columns 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Columns 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Columns 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Columns 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Columns 5"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 5"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 6"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 7"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Grid 8"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 4"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 5"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 6"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 7"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table List 8"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table 3D effects 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table 3D effects 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table 3D effects 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Contemporary"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Elegant"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Professional"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Subtle 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Subtle 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Web 1"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Web 2"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Web 3"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Balloon Text"/> <w:LsdException Locked="false" Priority="39" Name="Table Grid"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Table Theme"/> <w:LsdException Locked="false" SemiHidden="true" Name="Placeholder Text"/> <w:LsdException Locked="false" Priority="1" QFormat="true" Name="No Spacing"/> <w:LsdException Locked="false" Priority="60" Name="Light Shading"/> <w:LsdException Locked="false" Priority="61" Name="Light List"/> <w:LsdException Locked="false" Priority="62" Name="Light Grid"/> <w:LsdException Locked="false" Priority="63" Name="Medium Shading 1"/> <w:LsdException Locked="false" Priority="64" Name="Medium Shading 2"/> <w:LsdException Locked="false" Priority="65" Name="Medium List 1"/> <w:LsdException Locked="false" Priority="66" Name="Medium List 2"/> <w:LsdException Locked="false" Priority="67" Name="Medium Grid 1"/> <w:LsdException Locked="false" Priority="68" Name="Medium Grid 2"/> <w:LsdException Locked="false" Priority="69" Name="Medium Grid 3"/> <w:LsdException Locked="false" Priority="70" Name="Dark List"/> <w:LsdException Locked="false" Priority="71" Name="Colorful Shading"/> <w:LsdException Locked="false" Priority="72" Name="Colorful List"/> <w:LsdException Locked="false" Priority="73" Name="Colorful Grid"/> <w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 1"/> <w:LsdException Locked="false" Priority="61" Name="Light List Accent 1"/> <w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 1"/> <w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 1"/> <w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 1"/> <w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 1"/> <w:LsdException Locked="false" SemiHidden="true" Name="Revision"/> <w:LsdException Locked="false" Priority="34" QFormat="true" Name="List Paragraph"/> <w:LsdException Locked="false" Priority="29" QFormat="true" Name="Quote"/> <w:LsdException Locked="false" Priority="30" QFormat="true" Name="Intense Quote"/> <w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 1"/> <w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 1"/> <w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 1"/> <w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 1"/> <w:LsdException Locked="false" Priority="70" Name="Dark List Accent 1"/> <w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 1"/> <w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 1"/> <w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 1"/> <w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 2"/> <w:LsdException Locked="false" Priority="61" Name="Light List Accent 2"/> <w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 2"/> <w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 2"/> <w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 2"/> <w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 2"/> <w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 2"/> <w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 2"/> <w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 2"/> <w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 2"/> <w:LsdException Locked="false" Priority="70" Name="Dark List Accent 2"/> <w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 2"/> <w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 2"/> <w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 2"/> <w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 3"/> <w:LsdException Locked="false" Priority="61" Name="Light List Accent 3"/> <w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 3"/> <w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 3"/> <w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 3"/> <w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 3"/> <w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 3"/> <w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 3"/> <w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 3"/> <w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 3"/> <w:LsdException Locked="false" Priority="70" Name="Dark List Accent 3"/> <w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 3"/> <w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 3"/> <w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 3"/> <w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 4"/> <w:LsdException Locked="false" Priority="61" Name="Light List Accent 4"/> <w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 4"/> <w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 4"/> <w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 4"/> <w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 4"/> <w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 4"/> <w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 4"/> <w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 4"/> <w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 4"/> <w:LsdException Locked="false" Priority="70" Name="Dark List Accent 4"/> <w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 4"/> <w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 4"/> <w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 4"/> <w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 5"/> <w:LsdException Locked="false" Priority="61" Name="Light List Accent 5"/> <w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 5"/> <w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 5"/> <w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 5"/> <w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 5"/> <w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 5"/> <w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 5"/> <w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 5"/> <w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 5"/> <w:LsdException Locked="false" Priority="70" Name="Dark List Accent 5"/> <w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 5"/> <w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 5"/> <w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 5"/> <w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 6"/> <w:LsdException Locked="false" Priority="61" Name="Light List Accent 6"/> <w:LsdException Locked="false" Priority="62" Name="Light Grid Accent 6"/> <w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 6"/> <w:LsdException Locked="false" Priority="64" Name="Medium Shading 2 Accent 6"/> <w:LsdException Locked="false" Priority="65" Name="Medium List 1 Accent 6"/> <w:LsdException Locked="false" Priority="66" Name="Medium List 2 Accent 6"/> <w:LsdException Locked="false" Priority="67" Name="Medium Grid 1 Accent 6"/> <w:LsdException Locked="false" Priority="68" Name="Medium Grid 2 Accent 6"/> <w:LsdException Locked="false" Priority="69" Name="Medium Grid 3 Accent 6"/> <w:LsdException Locked="false" Priority="70" Name="Dark List Accent 6"/> <w:LsdException Locked="false" Priority="71" Name="Colorful Shading Accent 6"/> <w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 6"/> <w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 6"/> <w:LsdException Locked="false" Priority="19" QFormat="true" Name="Subtle Emphasis"/> <w:LsdException Locked="false" Priority="21" QFormat="true" Name="Intense Emphasis"/> <w:LsdException Locked="false" Priority="31" QFormat="true" Name="Subtle Reference"/> <w:LsdException Locked="false" Priority="32" QFormat="true" Name="Intense Reference"/> <w:LsdException Locked="false" Priority="33" QFormat="true" Name="Book Title"/> <w:LsdException Locked="false" Priority="37" SemiHidden="true" UnhideWhenUsed="true" Name="Bibliography"/> <w:LsdException Locked="false" Priority="39" SemiHidden="true" UnhideWhenUsed="true" QFormat="true" Name="TOC Heading"/> <w:LsdException Locked="false" Priority="41" Name="Plain Table 1"/> <w:LsdException Locked="false" Priority="42" Name="Plain Table 2"/> <w:LsdException Locked="false" Priority="43" Name="Plain Table 3"/> <w:LsdException Locked="false" Priority="44" Name="Plain Table 4"/> <w:LsdException Locked="false" Priority="45" Name="Plain Table 5"/> <w:LsdException Locked="false" Priority="40" Name="Grid Table Light"/> <w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light"/> <w:LsdException Locked="false" Priority="47" Name="Grid Table 2"/> <w:LsdException Locked="false" Priority="48" Name="Grid Table 3"/> <w:LsdException Locked="false" Priority="49" Name="Grid Table 4"/> <w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark"/> <w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful"/> <w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful"/> <w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 1"/> <w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 1"/> <w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 1"/> <w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 1"/> <w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 1"/> <w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 1"/> <w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 1"/> <w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 2"/> <w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 2"/> <w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 2"/> <w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 2"/> <w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 2"/> <w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 2"/> <w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 2"/> <w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 3"/> <w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 3"/> <w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 3"/> <w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 3"/> <w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 3"/> <w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 3"/> <w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 3"/> <w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 4"/> <w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 4"/> <w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 4"/> <w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 4"/> <w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 4"/> <w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 4"/> <w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 4"/> <w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 5"/> <w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 5"/> <w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 5"/> <w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 5"/> <w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 5"/> <w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 5"/> <w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 5"/> <w:LsdException Locked="false" Priority="46" Name="Grid Table 1 Light Accent 6"/> <w:LsdException Locked="false" Priority="47" Name="Grid Table 2 Accent 6"/> <w:LsdException Locked="false" Priority="48" Name="Grid Table 3 Accent 6"/> <w:LsdException Locked="false" Priority="49" Name="Grid Table 4 Accent 6"/> <w:LsdException Locked="false" Priority="50" Name="Grid Table 5 Dark Accent 6"/> <w:LsdException Locked="false" Priority="51" Name="Grid Table 6 Colorful Accent 6"/> <w:LsdException Locked="false" Priority="52" Name="Grid Table 7 Colorful Accent 6"/> <w:LsdException Locked="false" Priority="46" Name="List Table 1 Light"/> <w:LsdException Locked="false" Priority="52" Name="List Table 2"/> <w:LsdException Locked="false" Priority="48" Name="List Table 3"/> <w:LsdException Locked="false" Priority="49" Name="List Table 4"/> <w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark"/> <w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful"/> <w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful"/> <w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 1"/> <w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 1"/> <w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 1"/> <w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 1"/> <w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 1"/> <w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 1"/> <w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 1"/> <w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 2"/> <w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 2"/> <w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 2"/> <w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 2"/> <w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 2"/> <w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 2"/> <w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 2"/> <w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 3"/> <w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 3"/> <w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 3"/> <w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 3"/> <w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 3"/> <w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 3"/> <w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 3"/> <w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 4"/> <w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 4"/> <w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 4"/> <w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 4"/> <w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 4"/> <w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 4"/> <w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 4"/> <w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 5"/> <w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 5"/> <w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 5"/> <w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 5"/> <w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 5"/> <w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 5"/> <w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 5"/> <w:LsdException Locked="false" Priority="46" Name="List Table 1 Light Accent 6"/> <w:LsdException Locked="false" Priority="47" Name="List Table 2 Accent 6"/> <w:LsdException Locked="false" Priority="48" Name="List Table 3 Accent 6"/> <w:LsdException Locked="false" Priority="49" Name="List Table 4 Accent 6"/> <w:LsdException Locked="false" Priority="50" Name="List Table 5 Dark Accent 6"/> <w:LsdException Locked="false" Priority="51" Name="List Table 6 Colorful Accent 6"/> <w:LsdException Locked="false" Priority="52" Name="List Table 7 Colorful Accent 6"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Mention"/> <w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true" Name="Smart Hyperlink"/> </w:LatentStyles> </xml><![endif]--> <style> <!-- /* Font Definitions */ @font-face {font-family:Wingdings; panose-1:5 0 0 0 0 0 0 0 0 0; mso-font-charset:2; mso-generic-font-family:decorative; mso-font-pitch:variable; mso-font-signature:0 268435456 0 0 -2147483648 0;} @font-face {font-family:"MS Mincho"; panose-1:2 2 6 9 4 2 5 8 3 4; mso-font-alt:"-3 fg"; mso-font-charset:128; mso-generic-font-family:modern; mso-font-pitch:fixed; mso-font-signature:-536870145 1791491579 134217746 0 131231 0;} @font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:3 0 0 0 1 0;} @font-face {font-family:Calibri; panose-1:2 15 5 2 2 2 4 3 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-536859905 -1073732485 9 0 511 0;} @font-face {font-family:Times; panose-1:0 0 5 0 0 0 0 2 0 0; mso-font-charset:0; mso-generic-font-family:auto; mso-font-pitch:variable; mso-font-signature:-536870145 1342185562 0 0 415 0;} @font-face {font-family:Tahoma; panose-1:2 11 6 4 3 5 4 4 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-520081665 -1073717157 41 0 66047 0;} @font-face {font-family:"Arial Narrow"; panose-1:2 11 6 6 2 2 2 3 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:647 2048 0 0 159 0;} @font-face {font-family:"\@MS Mincho"; panose-1:2 2 6 9 4 2 5 8 3 4; mso-font-charset:128; mso-generic-font-family:modern; mso-font-pitch:fixed; mso-font-signature:-536870145 1791491579 134217746 0 131231 0;} /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin-top:0cm; margin-right:0cm; margin-bottom:8.0pt; margin-left:0cm; line-height:105%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} h1 {mso-style-priority:9; mso-style-unhide:no; mso-style-qformat:yes; mso-style-link:"Ttulo 1 Car"; mso-margin-top-alt:auto; margin-right:0cm; mso-margin-bottom-alt:auto; margin-left:0cm; mso-pagination:widow-orphan; mso-outline-level:1; font-size:24.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:ES; mso-fareast-language:ES; font-weight:bold;} h2 {mso-style-noshow:yes; mso-style-priority:9; mso-style-qformat:yes; mso-style-link:"Ttulo 2 Car"; mso-style-next:Normal; margin-top:2.0pt; margin-right:0cm; margin-bottom:0cm; margin-left:0cm; margin-bottom:.0001pt; line-height:105%; mso-pagination:widow-orphan lines-together; page-break-after:avoid; mso-outline-level:2; font-size:13.0pt; font-family:"Calibri Light",sans-serif; mso-ascii-font-family:"Calibri Light"; mso-ascii-theme-font:major-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:major-fareast; mso-hansi-font-family:"Calibri Light"; mso-hansi-theme-font:major-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:major-bidi; color:#2F5496; mso-themecolor:accent1; mso-themeshade:191; mso-ansi-language:ES; mso-fareast-language:EN-US; font-weight:normal;} h3 {mso-style-noshow:yes; mso-style-priority:9; mso-style-qformat:yes; mso-style-link:"Ttulo 3 Car"; mso-style-next:Normal; margin-top:2.0pt; margin-right:0cm; margin-bottom:0cm; margin-left:0cm; margin-bottom:.0001pt; line-height:105%; mso-pagination:widow-orphan lines-together; page-break-after:avoid; mso-outline-level:3; font-size:12.0pt; font-family:"Calibri Light",sans-serif; mso-ascii-font-family:"Calibri Light"; mso-ascii-theme-font:major-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:major-fareast; mso-hansi-font-family:"Calibri Light"; mso-hansi-theme-font:major-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:major-bidi; color:#1F3763; mso-themecolor:accent1; mso-themeshade:127; mso-ansi-language:ES; mso-fareast-language:EN-US; font-weight:normal;} p.MsoFootnoteText, li.MsoFootnoteText, div.MsoFootnoteText {mso-style-link:"Texto nota pie Car"; margin:0cm; margin-bottom:.0001pt; mso-pagination:none; text-autospace:none; font-size:10.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-US; mso-fareast-language:EN-US;} p.MsoCommentText, li.MsoCommentText, div.MsoCommentText {mso-style-noshow:yes; mso-style-priority:99; mso-style-link:"Texto comentario Car"; margin-top:0cm; margin-right:0cm; margin-bottom:8.0pt; margin-left:0cm; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} p.MsoHeader, li.MsoHeader, div.MsoHeader {mso-style-priority:99; mso-style-link:"Encabezado Car"; margin:0cm; margin-bottom:.0001pt; mso-pagination:widow-orphan; tab-stops:center 234.0pt right 468.0pt; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} p.MsoFooter, li.MsoFooter, div.MsoFooter {mso-style-priority:99; mso-style-link:"Pie de pgina Car"; margin:0cm; margin-bottom:.0001pt; mso-pagination:widow-orphan; tab-stops:center 234.0pt right 468.0pt; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} p.MsoCaption, li.MsoCaption, div.MsoCaption {mso-style-noshow:yes; mso-style-priority:35; mso-style-qformat:yes; mso-style-next:Normal; margin-top:0cm; margin-right:0cm; margin-bottom:10.0pt; margin-left:0cm; mso-pagination:widow-orphan; font-size:9.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; color:#44546A; mso-themecolor:text2; mso-ansi-language:ES; mso-fareast-language:EN-US; font-style:italic;} span.MsoFootnoteReference {mso-style-noshow:yes; vertical-align:super;} span.MsoCommentReference {mso-style-noshow:yes; mso-style-priority:99; mso-ansi-font-size:8.0pt; mso-bidi-font-size:8.0pt;} p.MsoBodyTextIndent, li.MsoBodyTextIndent, div.MsoBodyTextIndent {mso-style-noshow:yes; mso-style-priority:99; mso-style-link:"Sangra de texto normal Car"; margin-top:8.0pt; margin-right:0cm; margin-bottom:6.0pt; margin-left:14.15pt; text-align:justify; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-fareast-font-family:"Times New Roman"; mso-bidi-font-family:"Times New Roman"; mso-ansi-language:X-NONE; mso-fareast-language:EN-US; mso-bidi-language:EN-US;} a:link, span.MsoHyperlink {mso-style-priority:99; color:#0563C1; mso-themecolor:hyperlink; text-decoration:underline; text-underline:single;} a:visited, span.MsoHyperlinkFollowed {mso-style-noshow:yes; mso-style-priority:99; color:#954F72; mso-themecolor:followedhyperlink; text-decoration:underline; text-underline:single;} p {mso-style-priority:99; mso-margin-top-alt:auto; margin-right:0cm; mso-margin-bottom-alt:auto; margin-left:0cm; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman"; mso-fareast-language:ES-EC;} pre {mso-style-noshow:yes; mso-style-priority:99; mso-style-link:"HTML con formato previo Car"; margin:0cm; margin-bottom:.0001pt; mso-pagination:widow-orphan; tab-stops:45.8pt 91.6pt 137.4pt 183.2pt 229.0pt 274.8pt 320.6pt 366.4pt 412.2pt 458.0pt 503.8pt 549.6pt 595.4pt 641.2pt 687.0pt 732.8pt; font-size:10.0pt; font-family:"Courier New"; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:ES; mso-fareast-language:ES;} p.MsoCommentSubject, li.MsoCommentSubject, div.MsoCommentSubject {mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:"Texto comentario"; mso-style-link:"Asunto del comentario Car"; mso-style-next:"Texto comentario"; margin-top:0cm; margin-right:0cm; margin-bottom:8.0pt; margin-left:0cm; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US; font-weight:bold;} p.MsoAcetate, li.MsoAcetate, div.MsoAcetate {mso-style-noshow:yes; mso-style-priority:99; mso-style-link:"Texto de globo Car"; margin:0cm; margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:9.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-ansi-language:ES; mso-fareast-language:EN-US;} p.MsoNoSpacing, li.MsoNoSpacing, div.MsoNoSpacing {mso-style-noshow:yes; mso-style-priority:1; mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; mso-style-link:"Sin espaciado Car"; margin:0cm; margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:ES;} p.MsoListParagraph, li.MsoListParagraph, div.MsoListParagraph {mso-style-name:"Prrafo de lista\,PDrrafo de lista\,Prrafo de lista1"; mso-style-priority:34; mso-style-unhide:no; mso-style-qformat:yes; mso-style-link:"Prrafo de lista Car\,PDrrafo de lista Car\,Prrafo de lista1 Car"; margin-top:0cm; margin-right:0cm; margin-bottom:8.0pt; margin-left:36.0pt; mso-add-space:auto; line-height:105%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} p.MsoListParagraphCxSpFirst, li.MsoListParagraphCxSpFirst, div.MsoListParagraphCxSpFirst {mso-style-name:"Prrafo de lista\,PDrrafo de lista\,Prrafo de lista1CxSpFirst"; mso-style-priority:34; mso-style-unhide:no; mso-style-qformat:yes; mso-style-link:"Prrafo de lista Car\,PDrrafo de lista Car\,Prrafo de lista1 Car"; mso-style-type:export-only; margin-top:0cm; margin-right:0cm; margin-bottom:0cm; margin-left:36.0pt; margin-bottom:.0001pt; mso-add-space:auto; line-height:105%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} p.MsoListParagraphCxSpMiddle, li.MsoListParagraphCxSpMiddle, div.MsoListParagraphCxSpMiddle {mso-style-name:"Prrafo de lista\,PDrrafo de lista\,Prrafo de lista1CxSpMiddle"; mso-style-priority:34; mso-style-unhide:no; mso-style-qformat:yes; mso-style-link:"Prrafo de lista Car\,PDrrafo de lista Car\,Prrafo de lista1 Car"; mso-style-type:export-only; margin-top:0cm; margin-right:0cm; margin-bottom:0cm; margin-left:36.0pt; margin-bottom:.0001pt; mso-add-space:auto; line-height:105%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} p.MsoListParagraphCxSpLast, li.MsoListParagraphCxSpLast, div.MsoListParagraphCxSpLast {mso-style-name:"Prrafo de lista\,PDrrafo de lista\,Prrafo de lista1CxSpLast"; mso-style-priority:34; mso-style-unhide:no; mso-style-qformat:yes; mso-style-link:"Prrafo de lista Car\,PDrrafo de lista Car\,Prrafo de lista1 Car"; mso-style-type:export-only; margin-top:0cm; margin-right:0cm; margin-bottom:8.0pt; margin-left:36.0pt; mso-add-space:auto; line-height:105%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} p.MsoQuote, li.MsoQuote, div.MsoQuote {mso-style-noshow:yes; mso-style-priority:29; mso-style-unhide:no; mso-style-qformat:yes; mso-style-link:"Cita Car"; mso-style-next:Normal; margin-top:0cm; margin-right:0cm; margin-bottom:0cm; margin-left:14.2pt; margin-bottom:.0001pt; text-align:justify; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Arial",sans-serif; mso-fareast-font-family:"Times New Roman"; color:black; mso-themecolor:text1; mso-ansi-language:ES; mso-fareast-language:ES-EC; mso-bidi-font-style:italic;} span.MsoBookTitle {mso-style-priority:33; mso-style-unhide:no; mso-style-qformat:yes; letter-spacing:.25pt; font-weight:bold; font-style:italic;} p.MsoBibliography, li.MsoBibliography, div.MsoBibliography {mso-style-noshow:yes; mso-style-priority:37; mso-style-next:Normal; margin-top:0cm; margin-right:0cm; margin-bottom:8.0pt; margin-left:0cm; line-height:105%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} p.MsoTocHeading, li.MsoTocHeading, div.MsoTocHeading {mso-style-noshow:yes; mso-style-priority:39; mso-style-qformat:yes; mso-style-parent:"Ttulo 1"; mso-style-next:Normal; margin-top:12.0pt; margin-right:0cm; margin-bottom:0cm; margin-left:0cm; margin-bottom:.0001pt; text-align:center; line-height:105%; mso-pagination:widow-orphan lines-together; page-break-after:avoid; font-size:16.0pt; font-family:"Calibri Light",sans-serif; mso-ascii-font-family:"Calibri Light"; mso-ascii-theme-font:major-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:major-fareast; mso-hansi-font-family:"Calibri Light"; mso-hansi-theme-font:major-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:major-bidi; color:#2F5496; mso-themecolor:accent1; mso-themeshade:191; mso-ansi-language:ES; mso-fareast-language:ES;} span.Ttulo1Car {mso-style-name:"Ttulo 1 Car"; mso-style-priority:9; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:"Ttulo 1"; mso-ansi-font-size:24.0pt; mso-bidi-font-size:24.0pt; font-family:"Times New Roman",serif; mso-ascii-font-family:"Times New Roman"; mso-fareast-font-family:"Times New Roman"; mso-hansi-font-family:"Times New Roman"; mso-bidi-font-family:"Times New Roman"; mso-font-kerning:18.0pt; mso-fareast-language:ES; font-weight:bold;} span.Ttulo2Car {mso-style-name:"Ttulo 2 Car"; mso-style-noshow:yes; mso-style-priority:9; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:"Ttulo 2"; mso-ansi-font-size:13.0pt; mso-bidi-font-size:13.0pt; font-family:"Calibri Light",sans-serif; mso-ascii-font-family:"Calibri Light"; mso-ascii-theme-font:major-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:major-fareast; mso-hansi-font-family:"Calibri Light"; mso-hansi-theme-font:major-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:major-bidi; color:#2F5496; mso-themecolor:accent1; mso-themeshade:191;} span.Ttulo3Car {mso-style-name:"Ttulo 3 Car"; mso-style-noshow:yes; mso-style-priority:9; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:"Ttulo 3"; mso-ansi-font-size:12.0pt; mso-bidi-font-size:12.0pt; font-family:"Calibri Light",sans-serif; mso-ascii-font-family:"Calibri Light"; mso-ascii-theme-font:major-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:major-fareast; mso-hansi-font-family:"Calibri Light"; mso-hansi-theme-font:major-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:major-bidi; color:#1F3763; mso-themecolor:accent1; mso-themeshade:127;} span.HTMLconformatoprevioCar {mso-style-name:"HTML con formato previo Car"; mso-style-noshow:yes; mso-style-priority:99; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:"HTML con formato previo"; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt; font-family:"Courier New"; mso-ascii-font-family:"Courier New"; mso-fareast-font-family:"Times New Roman"; mso-hansi-font-family:"Courier New"; mso-bidi-font-family:"Courier New"; mso-fareast-language:ES;} p.msonormal0, li.msonormal0, div.msonormal0 {mso-style-name:msonormal; mso-style-priority:99; mso-style-unhide:no; mso-margin-top-alt:auto; margin-right:0cm; mso-margin-bottom-alt:auto; margin-left:0cm; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman"; mso-fareast-language:ES-EC;} span.TextonotapieCar {mso-style-name:"Texto nota pie Car"; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:"Texto nota pie"; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt; font-family:"Times New Roman",serif; mso-ascii-font-family:"Times New Roman"; mso-fareast-font-family:"Times New Roman"; mso-hansi-font-family:"Times New Roman"; mso-bidi-font-family:"Times New Roman"; mso-ansi-language:EN-US;} span.TextocomentarioCar {mso-style-name:"Texto comentario Car"; mso-style-noshow:yes; mso-style-priority:99; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:"Texto comentario"; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt;} span.EncabezadoCar {mso-style-name:"Encabezado Car"; mso-style-priority:99; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:Encabezado;} span.PiedepginaCar {mso-style-name:"Pie de pgina Car"; mso-style-priority:99; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:"Pie de pgina";} span.SangradetextonormalCar {mso-style-name:"Sangra de texto normal Car"; mso-style-noshow:yes; mso-style-priority:99; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:"Sangra de texto normal"; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-fareast-font-family:"Times New Roman"; mso-hansi-font-family:Calibri; mso-bidi-font-family:"Times New Roman"; mso-ansi-language:X-NONE; mso-bidi-language:EN-US;} span.AsuntodelcomentarioCar {mso-style-name:"Asunto del comentario Car"; mso-style-noshow:yes; mso-style-priority:99; mso-style-unhide:no; mso-style-locked:yes; mso-style-parent:"Texto comentario Car"; mso-style-link:"Asunto del comentario"; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt; font-weight:bold;} span.TextodegloboCar {mso-style-name:"Texto de globo Car"; mso-style-noshow:yes; mso-style-priority:99; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:"Texto de globo"; mso-ansi-font-size:9.0pt; mso-bidi-font-size:9.0pt; font-family:"Times New Roman",serif; mso-ascii-font-family:"Times New Roman"; mso-hansi-font-family:"Times New Roman"; mso-bidi-font-family:"Times New Roman";} span.SinespaciadoCar {mso-style-name:"Sin espaciado Car"; mso-style-priority:1; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:"Sin espaciado"; font-family:"MS Mincho"; mso-ascii-font-family:"MS Mincho"; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:"MS Mincho"; mso-fareast-language:ES;} span.PrrafodelistaCar {mso-style-name:"Prrafo de lista Car\,PDrrafo de lista Car\,Prrafo de lista1 Car"; mso-style-priority:34; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:"Prrafo de lista\,PDrrafo de lista\,Prrafo de lista1";} span.CitaCar {mso-style-name:"Cita Car"; mso-style-priority:29; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:Cita; mso-ansi-font-size:12.0pt; mso-bidi-font-size:12.0pt; font-family:"Arial",sans-serif; mso-ascii-font-family:Arial; mso-fareast-font-family:"Times New Roman"; mso-hansi-font-family:Arial; mso-bidi-font-family:Arial; color:black; mso-themecolor:text1; mso-fareast-language:ES-EC; mso-bidi-font-style:italic;} p.xmsonormal, li.xmsonormal, div.xmsonormal {mso-style-name:x_msonormal; mso-style-noshow:yes; mso-style-priority:99; mso-style-unhide:no; mso-margin-top-alt:auto; margin-right:0cm; mso-margin-bottom-alt:auto; margin-left:0cm; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:ES; mso-fareast-language:ES;} span.ANGLESCar {mso-style-name:"ANGLES Car"; mso-style-unhide:no; mso-style-locked:yes; mso-style-parent:""; mso-style-link:ANGLES; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt; font-family:"Arial",sans-serif; mso-ascii-font-family:Arial; mso-fareast-font-family:"Times New Roman"; mso-hansi-font-family:Arial; mso-bidi-font-family:"Times New Roman"; mso-ansi-language:X-NONE; mso-fareast-language:X-NONE;} p.ANGLES, li.ANGLES, div.ANGLES {mso-style-name:ANGLES; mso-style-priority:99; mso-style-unhide:no; mso-style-qformat:yes; mso-style-link:"ANGLES Car"; margin-top:8.0pt; margin-right:0cm; margin-bottom:6.0pt; margin-left:0cm; text-align:justify; line-height:115%; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Arial",sans-serif; mso-fareast-font-family:"Times New Roman"; mso-bidi-font-family:"Times New Roman"; mso-ansi-language:X-NONE; mso-fareast-language:X-NONE;} p.paragraph, li.paragraph, div.paragraph {mso-style-name:paragraph; mso-style-noshow:yes; mso-style-priority:99; mso-style-unhide:no; mso-margin-top-alt:auto; margin-right:0cm; mso-margin-bottom-alt:auto; margin-left:0cm; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman"; mso-fareast-language:ES-EC;} p.TableParagraph, li.TableParagraph, div.TableParagraph {mso-style-name:"Table Paragraph"; mso-style-noshow:yes; mso-style-priority:1; mso-style-unhide:no; mso-style-qformat:yes; margin-top:.8pt; margin-right:0cm; margin-bottom:0cm; margin-left:0cm; margin-bottom:.0001pt; mso-pagination:none; font-size:12.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-US; mso-fareast-language:ES-EC;} p.Default, li.Default, div.Default {mso-style-name:Default; mso-style-noshow:yes; mso-style-priority:99; mso-style-unhide:no; mso-style-parent:""; margin:0cm; margin-bottom:.0001pt; mso-pagination:widow-orphan; mso-layout-grid-align:none; text-autospace:none; font-size:12.0pt; font-family:"Arial",sans-serif; mso-fareast-font-family:"Times New Roman"; color:black; mso-ansi-language:ES; mso-fareast-language:ES;} span.AutorCar {mso-style-name:"Autor Car"; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:Autor; mso-ansi-font-size:14.0pt; font-family:"Arial",sans-serif; mso-ascii-font-family:Arial; mso-hansi-font-family:Arial; mso-bidi-font-family:Arial;} p.Autor, li.Autor, div.Autor {mso-style-name:Autor; mso-style-priority:99; mso-style-unhide:no; mso-style-qformat:yes; mso-style-link:"Autor Car"; mso-style-next:Normal; margin-top:6.0pt; margin-right:0cm; margin-bottom:3.0pt; margin-left:0cm; text-align:right; mso-pagination:widow-orphan; font-size:14.0pt; mso-bidi-font-size:11.0pt; font-family:"Arial",sans-serif; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} span.AfiliacinCar {mso-style-name:"Afiliacin Car"; mso-style-unhide:no; mso-style-locked:yes; mso-style-link:Afiliacin; mso-ansi-font-size:12.0pt; font-family:"Arial",sans-serif; mso-ascii-font-family:Arial; mso-hansi-font-family:Arial; mso-bidi-font-family:Arial;} p.Afiliacin, li.Afiliacin, div.Afiliacin {mso-style-name:Afiliacin; mso-style-priority:99; mso-style-unhide:no; mso-style-qformat:yes; mso-style-link:"Afiliacin Car"; margin:0cm; margin-bottom:.0001pt; text-align:right; mso-pagination:widow-orphan; font-size:12.0pt; mso-bidi-font-size:11.0pt; font-family:"Arial",sans-serif; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} span.Cuadrculavistosa-nfasis1Car {mso-style-name:"Cuadrcula vistosa - nfasis 1 Car"; mso-style-priority:29; mso-style-unhide:no; mso-style-locked:yes; mso-style-parent:""; mso-style-link:"Cuadrcula vistosa - nfasis 11"; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt; font-family:"Arial",sans-serif; mso-ascii-font-family:Arial; mso-fareast-font-family:"Times New Roman"; mso-hansi-font-family:Arial; mso-bidi-font-family:"Times New Roman"; color:black; mso-ansi-language:X-NONE; mso-fareast-language:X-NONE; font-style:italic;} p.Cuadrculavistosa-nfasis11, li.Cuadrculavistosa-nfasis11, div.Cuadrculavistosa-nfasis11 {mso-style-name:"Cuadrcula vistosa - nfasis 11"; mso-style-priority:29; mso-style-unhide:no; mso-style-qformat:yes; mso-style-link:"Cuadrcula vistosa - nfasis 1 Car"; mso-style-next:Normal; margin-top:8.0pt; margin-right:0cm; margin-bottom:6.0pt; margin-left:0cm; text-align:justify; line-height:115%; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Arial",sans-serif; mso-fareast-font-family:"Times New Roman"; mso-bidi-font-family:"Times New Roman"; color:black; mso-ansi-language:X-NONE; mso-fareast-language:X-NONE; font-style:italic;} span.Mencinsinresolver1 {mso-style-name:"Mencin sin resolver1"; mso-style-noshow:yes; mso-style-priority:99; mso-style-unhide:no; color:#605E5C; background:#E1DFDD;} span.il {mso-style-name:il; mso-style-unhide:no;} span.orcid-id-https {mso-style-name:orcid-id-https; mso-style-unhide:no;} span.hps {mso-style-name:hps; mso-style-unhide:no;} span.Tablanormal31 {mso-style-name:"Tabla normal 31"; mso-style-priority:19; mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; color:gray; font-style:italic;} span.orcid-id-https2 {mso-style-name:orcid-id-https2; mso-style-unhide:no; mso-ansi-font-size:9.0pt; mso-bidi-font-size:9.0pt;} span.st {mso-style-name:st; mso-style-unhide:no;} span.tlid-translation {mso-style-name:tlid-translation; mso-style-unhide:no;} span.SpellE {mso-style-name:""; mso-spl-e:yes;} span.GramE {mso-style-name:""; mso-gram-e:yes;} .MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:11.0pt; mso-ansi-font-size:11.0pt; mso-bidi-font-size:11.0pt; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} /* Page Definitions */ @page {mso-footnote-separator:url("listo.fld/header.html") fs; mso-footnote-continuation-separator:url("listo.fld/header.html") fcs; mso-endnote-separator:url("listo.fld/header.html") es; mso-endnote-continuation-separator:url("listo.fld/header.html") ecs; mso-facing-pages:yes;} @page WordSection1 {size:595.3pt 841.9pt; margin:161.2pt 72.0pt 104.2pt 72.0pt; mso-header-margin:35.4pt; mso-footer-margin:35.4pt; mso-page-numbers:201; mso-title-page:yes; mso-even-header:url("listo.fld/header.html") eh1; mso-header:url("listo.fld/header.html") h1; mso-even-footer:url("listo.fld/header.html") ef1; mso-footer:url("listo.fld/header.html") f1; mso-first-header:url("listo.fld/header.html") fh1; mso-first-footer:url("listo.fld/header.html") ff1; mso-paper-source:0;} div.WordSection1 {page:WordSection1;} /* List Definitions */ @list l0 {mso-list-id:19136771; mso-list-type:hybrid; mso-list-template-ids:94288056 805961729 805961731 805961733 805961729 805961731 805961733 805961729 805961731 805961733;} @list l0:level1 {mso-level-number-format:bullet; mso-level-text:; mso-level-tab-stop:none; mso-level-number-position:left; text-indent:-18.0pt; font-family:Symbol;} @list l0:level2 {mso-level-number-format:bullet; mso-level-text:o; mso-level-tab-stop:none; mso-level-number-position:left; text-indent:-18.0pt; font-family:"Courier New";} @list l0:level3 {mso-level-number-format:bullet; mso-level-text:; mso-level-tab-stop:none; mso-level-number-position:left; text-indent:-18.0pt; font-family:Wingdings;} @list l0:level4 {mso-level-number-format:bullet; mso-level-text:; mso-level-tab-stop:none; mso-level-number-position:left; text-indent:-18.0pt; font-family:Symbol;} @list l0:level5 {mso-level-number-format:bullet; mso-level-text:o; mso-level-tab-stop:none; mso-level-number-position:left; text-indent:-18.0pt; font-family:"Courier New";} @list l0:level6 {mso-level-number-format:bullet; mso-level-text:; mso-level-tab-stop:none; mso-level-number-position:left; text-indent:-18.0pt; font-family:Wingdings;} @list l0:level7 {mso-level-number-format:bullet; mso-level-text:; mso-level-tab-stop:none; mso-level-number-position:left; text-indent:-18.0pt; font-family:Symbol;} @list l0:level8 {mso-level-number-format:bullet; mso-level-text:o; mso-level-tab-stop:none; mso-level-number-position:left; text-indent:-18.0pt; font-family:"Courier New";} @list l0:level9 {mso-level-number-format:bullet; mso-level-text:; mso-level-tab-stop:none; mso-level-number-position:left; text-indent:-18.0pt; font-family:Wingdings;} @list l1 {mso-list-id:128936702; mso-list-type:hybrid; mso-list-template-ids:1474182664 67764239 67764249 67764251 67764239 67764249 67764251 67764239 67764249 67764251;} @list l1:level1 {mso-level-tab-stop:none; mso-level-number-position:left; text-indent:-18.0pt;} @list l1:level2 {mso-level-number-format:alpha-lower; mso-level-tab-stop:none; mso-level-number-position:left; text-indent:-18.0pt;} @list l1:level3 {mso-level-number-format:roman-lower; mso-level-tab-stop:none; mso-level-number-position:right; text-indent:-9.0pt;} @list l1:level4 {mso-level-tab-stop:none; mso-level-number-position:left; text-indent:-18.0pt;} @list l1:level5 {mso-level-number-format:alpha-lower; mso-level-tab-stop:none; mso-level-number-position:left; text-indent:-18.0pt;} @list l1:level6 {mso-level-number-format:roman-lower; mso-level-tab-stop:none; mso-level-number-position:right; text-indent:-9.0pt;} @list l1:level7 {mso-level-tab-stop:none; mso-level-number-position:left; text-indent:-18.0pt;} @list l1:level8 {mso-level-number-format:alpha-lower; mso-level-tab-stop:none; mso-level-number-position:left; text-indent:-18.0pt;} @list l1:level9 {mso-level-number-format:roman-lower; mso-level-tab-stop:none; mso-level-number-position:right; text-indent:-9.0pt;} ol {margin-bottom:0cm;} ul {margin-bottom:0cm;} --> </style> <!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} table.MsoTableGrid {mso-style-name:"Tabla con cuadrcula"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-priority:39; mso-style-unhide:no; border:solid windowtext 1.0pt; mso-border-alt:solid windowtext .5pt; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-border-insideh:.5pt solid windowtext; mso-border-insidev:.5pt solid windowtext; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} table.MsoTableLightShading {mso-style-name:"Sombreado claro"; mso-tstyle-rowband-size:1; mso-tstyle-colband-size:1; mso-style-noshow:yes; mso-style-priority:60; border-top:solid black 1.0pt; mso-border-top-themecolor:text1; border-left:none; border-bottom:solid black 1.0pt; mso-border-bottom-themecolor:text1; border-right:none; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; color:black; mso-themecolor:text1; mso-themeshade:191; mso-ansi-language:ES; mso-fareast-language:EN-US;} table.MsoTableLightShadingFirstRow {mso-style-name:"Sombreado claro"; mso-table-condition:first-row; mso-style-noshow:yes; mso-style-priority:60; mso-tstyle-border-top:1.0pt solid black; mso-tstyle-border-top-themecolor:text1; mso-tstyle-border-left:cell-none; mso-tstyle-border-bottom:1.0pt solid black; mso-tstyle-border-bottom-themecolor:text1; mso-tstyle-border-right:cell-none; mso-tstyle-border-insideh:cell-none; mso-tstyle-border-insidev:cell-none; mso-para-margin-top:auto; mso-para-margin-bottom:auto; line-height:normal; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTableLightShadingLastRow {mso-style-name:"Sombreado claro"; mso-table-condition:last-row; mso-style-noshow:yes; mso-style-priority:60; mso-tstyle-border-top:1.0pt solid black; mso-tstyle-border-top-themecolor:text1; mso-tstyle-border-left:cell-none; mso-tstyle-border-bottom:1.0pt solid black; mso-tstyle-border-bottom-themecolor:text1; mso-tstyle-border-right:cell-none; mso-tstyle-border-insideh:cell-none; mso-tstyle-border-insidev:cell-none; mso-para-margin-top:auto; mso-para-margin-bottom:auto; line-height:normal; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTableLightShadingFirstCol {mso-style-name:"Sombreado claro"; mso-table-condition:first-column; mso-style-noshow:yes; mso-style-priority:60; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTableLightShadingLastCol {mso-style-name:"Sombreado claro"; mso-table-condition:last-column; mso-style-noshow:yes; mso-style-priority:60; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTableLightShadingOddColumn {mso-style-name:"Sombreado claro"; mso-table-condition:odd-column; mso-style-noshow:yes; mso-style-priority:60; mso-tstyle-shading:silver; mso-tstyle-shading-themecolor:text1; mso-tstyle-shading-themetint:63; mso-tstyle-border-left:cell-none; mso-tstyle-border-right:cell-none; mso-tstyle-border-insideh:cell-none; mso-tstyle-border-insidev:cell-none;} table.MsoTableLightShadingOddRow {mso-style-name:"Sombreado claro"; mso-table-condition:odd-row; mso-style-noshow:yes; mso-style-priority:60; mso-tstyle-shading:silver; mso-tstyle-shading-themecolor:text1; mso-tstyle-shading-themetint:63; mso-tstyle-border-left:cell-none; mso-tstyle-border-right:cell-none; mso-tstyle-border-insideh:cell-none; mso-tstyle-border-insidev:cell-none;} table.MsoTable15Plain3 {mso-style-name:"Tabla normal 3"; mso-tstyle-rowband-size:1; mso-tstyle-colband-size:1; mso-style-priority:43; mso-style-unhide:no; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} table.MsoTable15Plain3FirstRow {mso-style-name:"Tabla normal 3"; mso-table-condition:first-row; mso-style-priority:43; mso-style-unhide:no; mso-tstyle-border-bottom:.5pt solid #7F7F7F; mso-tstyle-border-bottom-themecolor:text1; mso-tstyle-border-bottom-themetint:128; text-transform:uppercase; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Plain3LastRow {mso-style-name:"Tabla normal 3"; mso-table-condition:last-row; mso-style-priority:43; mso-style-unhide:no; mso-tstyle-border-top:cell-none; text-transform:uppercase; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Plain3FirstCol {mso-style-name:"Tabla normal 3"; mso-table-condition:first-column; mso-style-priority:43; mso-style-unhide:no; mso-tstyle-border-right:.5pt solid #7F7F7F; mso-tstyle-border-right-themecolor:text1; mso-tstyle-border-right-themetint:128; text-transform:uppercase; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Plain3LastCol {mso-style-name:"Tabla normal 3"; mso-table-condition:last-column; mso-style-priority:43; mso-style-unhide:no; mso-tstyle-border-left:cell-none; text-transform:uppercase; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Plain3OddColumn {mso-style-name:"Tabla normal 3"; mso-table-condition:odd-column; mso-style-priority:43; mso-style-unhide:no; mso-tstyle-shading:#F2F2F2; mso-tstyle-shading-themecolor:background1; mso-tstyle-shading-themeshade:242;} table.MsoTable15Plain3OddRow {mso-style-name:"Tabla normal 3"; mso-table-condition:odd-row; mso-style-priority:43; mso-style-unhide:no; mso-tstyle-shading:#F2F2F2; mso-tstyle-shading-themecolor:background1; mso-tstyle-shading-themeshade:242;} table.MsoTable15Plain3NECell {mso-style-name:"Tabla normal 3"; mso-table-condition:ne-cell; mso-style-priority:43; mso-style-unhide:no; mso-tstyle-border-left:cell-none;} table.MsoTable15Plain3NWCell {mso-style-name:"Tabla normal 3"; mso-table-condition:nw-cell; mso-style-priority:43; mso-style-unhide:no; mso-tstyle-border-right:cell-none;} table.MsoTable15Grid4Accent1 {mso-style-name:"Tabla con cuadrcula 4 - nfasis 1"; mso-tstyle-rowband-size:1; mso-tstyle-colband-size:1; mso-style-priority:49; mso-style-unhide:no; border:solid #8EAADB 1.0pt; mso-border-themecolor:accent1; mso-border-themetint:153; mso-border-alt:solid #8EAADB .5pt; mso-border-themecolor:accent1; mso-border-themetint:153; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-border-insideh:.5pt solid #8EAADB; mso-border-insideh-themecolor:accent1; mso-border-insideh-themetint:153; mso-border-insidev:.5pt solid #8EAADB; mso-border-insidev-themecolor:accent1; mso-border-insidev-themetint:153; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} table.MsoTable15Grid4Accent1FirstRow {mso-style-name:"Tabla con cuadrcula 4 - nfasis 1"; mso-table-condition:first-row; mso-style-priority:49; mso-style-unhide:no; mso-tstyle-shading:#4472C4; mso-tstyle-shading-themecolor:accent1; mso-tstyle-border-top:.5pt solid #4472C4; mso-tstyle-border-top-themecolor:accent1; mso-tstyle-border-left:.5pt solid #4472C4; mso-tstyle-border-left-themecolor:accent1; mso-tstyle-border-bottom:.5pt solid #4472C4; mso-tstyle-border-bottom-themecolor:accent1; mso-tstyle-border-right:.5pt solid #4472C4; mso-tstyle-border-right-themecolor:accent1; mso-tstyle-border-insideh:cell-none; mso-tstyle-border-insidev:cell-none; color:white; mso-themecolor:background1; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Grid4Accent1LastRow {mso-style-name:"Tabla con cuadrcula 4 - nfasis 1"; mso-table-condition:last-row; mso-style-priority:49; mso-style-unhide:no; mso-tstyle-border-top:1.5pt double #4472C4; mso-tstyle-border-top-themecolor:accent1; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Grid4Accent1FirstCol {mso-style-name:"Tabla con cuadrcula 4 - nfasis 1"; mso-table-condition:first-column; mso-style-priority:49; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Grid4Accent1LastCol {mso-style-name:"Tabla con cuadrcula 4 - nfasis 1"; mso-table-condition:last-column; mso-style-priority:49; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Grid4Accent1OddColumn {mso-style-name:"Tabla con cuadrcula 4 - nfasis 1"; mso-table-condition:odd-column; mso-style-priority:49; mso-style-unhide:no; mso-tstyle-shading:#D9E2F3; mso-tstyle-shading-themecolor:accent1; mso-tstyle-shading-themetint:51;} table.MsoTable15Grid4Accent1OddRow {mso-style-name:"Tabla con cuadrcula 4 - nfasis 1"; mso-table-condition:odd-row; mso-style-priority:49; mso-style-unhide:no; mso-tstyle-shading:#D9E2F3; mso-tstyle-shading-themecolor:accent1; mso-tstyle-shading-themetint:51;} table.MsoTable15Grid6ColorfulAccent1 {mso-style-name:"Tabla con cuadrcula 6 con colores - nfasis 1"; mso-tstyle-rowband-size:1; mso-tstyle-colband-size:1; mso-style-priority:51; mso-style-unhide:no; border:solid #8EAADB 1.0pt; mso-border-themecolor:accent1; mso-border-themetint:153; mso-border-alt:solid #8EAADB .5pt; mso-border-themecolor:accent1; mso-border-themetint:153; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-border-insideh:.5pt solid #8EAADB; mso-border-insideh-themecolor:accent1; mso-border-insideh-themetint:153; mso-border-insidev:.5pt solid #8EAADB; mso-border-insidev-themecolor:accent1; mso-border-insidev-themetint:153; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; color:#2F5496; mso-themecolor:accent1; mso-themeshade:191; mso-ansi-language:ES; mso-fareast-language:EN-US;} table.MsoTable15Grid6ColorfulAccent1FirstRow {mso-style-name:"Tabla con cuadrcula 6 con colores - nfasis 1"; mso-table-condition:first-row; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-border-bottom:1.5pt solid #8EAADB; mso-tstyle-border-bottom-themecolor:accent1; mso-tstyle-border-bottom-themetint:153; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Grid6ColorfulAccent1LastRow {mso-style-name:"Tabla con cuadrcula 6 con colores - nfasis 1"; mso-table-condition:last-row; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-border-top:1.5pt double #8EAADB; mso-tstyle-border-top-themecolor:accent1; mso-tstyle-border-top-themetint:153; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Grid6ColorfulAccent1FirstCol {mso-style-name:"Tabla con cuadrcula 6 con colores - nfasis 1"; mso-table-condition:first-column; mso-style-priority:51; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Grid6ColorfulAccent1LastCol {mso-style-name:"Tabla con cuadrcula 6 con colores - nfasis 1"; mso-table-condition:last-column; mso-style-priority:51; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Grid6ColorfulAccent1OddColumn {mso-style-name:"Tabla con cuadrcula 6 con colores - nfasis 1"; mso-table-condition:odd-column; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-shading:#D9E2F3; mso-tstyle-shading-themecolor:accent1; mso-tstyle-shading-themetint:51;} table.MsoTable15Grid6ColorfulAccent1OddRow {mso-style-name:"Tabla con cuadrcula 6 con colores - nfasis 1"; mso-table-condition:odd-row; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-shading:#D9E2F3; mso-tstyle-shading-themecolor:accent1; mso-tstyle-shading-themetint:51;} table.MsoTable15Grid4Accent5 {mso-style-name:"Tabla con cuadrcula 4 - nfasis 5"; mso-tstyle-rowband-size:1; mso-tstyle-colband-size:1; mso-style-priority:49; mso-style-unhide:no; border:solid #9CC2E5 1.0pt; mso-border-themecolor:accent5; mso-border-themetint:153; mso-border-alt:solid #9CC2E5 .5pt; mso-border-themecolor:accent5; mso-border-themetint:153; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-border-insideh:.5pt solid #9CC2E5; mso-border-insideh-themecolor:accent5; mso-border-insideh-themetint:153; mso-border-insidev:.5pt solid #9CC2E5; mso-border-insidev-themecolor:accent5; mso-border-insidev-themetint:153; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} table.MsoTable15Grid4Accent5FirstRow {mso-style-name:"Tabla con cuadrcula 4 - nfasis 5"; mso-table-condition:first-row; mso-style-priority:49; mso-style-unhide:no; mso-tstyle-shading:#5B9BD5; mso-tstyle-shading-themecolor:accent5; mso-tstyle-border-top:.5pt solid #5B9BD5; mso-tstyle-border-top-themecolor:accent5; mso-tstyle-border-left:.5pt solid #5B9BD5; mso-tstyle-border-left-themecolor:accent5; mso-tstyle-border-bottom:.5pt solid #5B9BD5; mso-tstyle-border-bottom-themecolor:accent5; mso-tstyle-border-right:.5pt solid #5B9BD5; mso-tstyle-border-right-themecolor:accent5; mso-tstyle-border-insideh:cell-none; mso-tstyle-border-insidev:cell-none; color:white; mso-themecolor:background1; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Grid4Accent5LastRow {mso-style-name:"Tabla con cuadrcula 4 - nfasis 5"; mso-table-condition:last-row; mso-style-priority:49; mso-style-unhide:no; mso-tstyle-border-top:1.5pt double #5B9BD5; mso-tstyle-border-top-themecolor:accent5; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Grid4Accent5FirstCol {mso-style-name:"Tabla con cuadrcula 4 - nfasis 5"; mso-table-condition:first-column; mso-style-priority:49; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Grid4Accent5LastCol {mso-style-name:"Tabla con cuadrcula 4 - nfasis 5"; mso-table-condition:last-column; mso-style-priority:49; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15Grid4Accent5OddColumn {mso-style-name:"Tabla con cuadrcula 4 - nfasis 5"; mso-table-condition:odd-column; mso-style-priority:49; mso-style-unhide:no; mso-tstyle-shading:#DEEAF6; mso-tstyle-shading-themecolor:accent5; mso-tstyle-shading-themetint:51;} table.MsoTable15Grid4Accent5OddRow {mso-style-name:"Tabla con cuadrcula 4 - nfasis 5"; mso-table-condition:odd-row; mso-style-priority:49; mso-style-unhide:no; mso-tstyle-shading:#DEEAF6; mso-tstyle-shading-themecolor:accent5; mso-tstyle-shading-themetint:51;} table.MsoTable15List2 {mso-style-name:"Tabla de lista 2"; mso-tstyle-rowband-size:1; mso-tstyle-colband-size:1; mso-style-priority:52; mso-style-unhide:no; border-top:solid #666666 1.0pt; mso-border-top-themecolor:text1; mso-border-top-themetint:153; border-left:none; border-bottom:solid #666666 1.0pt; mso-border-bottom-themecolor:text1; mso-border-bottom-themetint:153; border-right:none; mso-border-top-alt:solid #666666 .5pt; mso-border-top-themecolor:text1; mso-border-top-themetint:153; mso-border-bottom-alt:solid #666666 .5pt; mso-border-bottom-themecolor:text1; mso-border-bottom-themetint:153; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-border-insideh:.5pt solid #666666; mso-border-insideh-themecolor:text1; mso-border-insideh-themetint:153; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Arial",sans-serif; mso-fareast-font-family:"Times New Roman"; mso-bidi-font-family:"Times New Roman"; mso-ansi-language:ES; mso-fareast-language:ES-EC;} table.MsoTable15List2FirstRow {mso-style-name:"Tabla de lista 2"; mso-table-condition:first-row; mso-style-priority:52; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15List2LastRow {mso-style-name:"Tabla de lista 2"; mso-table-condition:last-row; mso-style-priority:52; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15List2FirstCol {mso-style-name:"Tabla de lista 2"; mso-table-condition:first-column; mso-style-priority:52; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15List2LastCol {mso-style-name:"Tabla de lista 2"; mso-table-condition:last-column; mso-style-priority:52; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15List2OddColumn {mso-style-name:"Tabla de lista 2"; mso-table-condition:odd-column; mso-style-priority:52; mso-style-unhide:no; mso-tstyle-shading:#CCCCCC; mso-tstyle-shading-themecolor:text1; mso-tstyle-shading-themetint:51;} table.MsoTable15List2OddRow {mso-style-name:"Tabla de lista 2"; mso-table-condition:odd-row; mso-style-priority:52; mso-style-unhide:no; mso-tstyle-shading:#CCCCCC; mso-tstyle-shading-themecolor:text1; mso-tstyle-shading-themetint:51;} table.MsoTable15List6Colorful {mso-style-name:"Tabla de lista 6 con colores"; mso-tstyle-rowband-size:1; mso-tstyle-colband-size:1; mso-style-priority:51; mso-style-unhide:no; border-top:solid black 1.0pt; mso-border-top-themecolor:text1; border-left:none; border-bottom:solid black 1.0pt; mso-border-bottom-themecolor:text1; border-right:none; mso-border-top-alt:solid black .5pt; mso-border-top-themecolor:text1; mso-border-bottom-alt:solid black .5pt; mso-border-bottom-themecolor:text1; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-fareast-font-family:Calibri; mso-bidi-font-family:"Times New Roman"; color:black; mso-themecolor:text1; mso-ansi-language:ES; mso-fareast-language:EN-US;} table.MsoTable15List6ColorfulFirstRow {mso-style-name:"Tabla de lista 6 con colores"; mso-table-condition:first-row; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-border-bottom:.5pt solid black; mso-tstyle-border-bottom-themecolor:text1; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15List6ColorfulLastRow {mso-style-name:"Tabla de lista 6 con colores"; mso-table-condition:last-row; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-border-top:1.5pt double black; mso-tstyle-border-top-themecolor:text1; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15List6ColorfulFirstCol {mso-style-name:"Tabla de lista 6 con colores"; mso-table-condition:first-column; mso-style-priority:51; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15List6ColorfulLastCol {mso-style-name:"Tabla de lista 6 con colores"; mso-table-condition:last-column; mso-style-priority:51; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.MsoTable15List6ColorfulOddColumn {mso-style-name:"Tabla de lista 6 con colores"; mso-table-condition:odd-column; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-shading:#CCCCCC; mso-tstyle-shading-themecolor:text1; mso-tstyle-shading-themetint:51;} table.MsoTable15List6ColorfulOddRow {mso-style-name:"Tabla de lista 6 con colores"; mso-table-condition:odd-row; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-shading:#CCCCCC; mso-tstyle-shading-themecolor:text1; mso-tstyle-shading-themetint:51;} table.Tablanormal41 {mso-style-name:"Tabla normal 41"; mso-tstyle-rowband-size:1; mso-tstyle-colband-size:1; mso-style-priority:99; mso-style-unhide:no; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} table.Tablanormal41FirstRow {mso-style-name:"Tabla normal 41"; mso-table-condition:first-row; mso-style-priority:99; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tablanormal41LastRow {mso-style-name:"Tabla normal 41"; mso-table-condition:last-row; mso-style-priority:99; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tablanormal41FirstCol {mso-style-name:"Tabla normal 41"; mso-table-condition:first-column; mso-style-priority:99; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tablanormal41LastCol {mso-style-name:"Tabla normal 41"; mso-table-condition:last-column; mso-style-priority:99; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tablanormal41OddColumn {mso-style-name:"Tabla normal 41"; mso-table-condition:odd-column; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-shading:#F2F2F2; mso-tstyle-shading-themecolor:background1; mso-tstyle-shading-themeshade:242;} table.Tablanormal41OddRow {mso-style-name:"Tabla normal 41"; mso-table-condition:odd-row; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-shading:#F2F2F2; mso-tstyle-shading-themecolor:background1; mso-tstyle-shading-themeshade:242;} table.Tablanormal51 {mso-style-name:"Tabla normal 51"; mso-tstyle-rowband-size:1; mso-tstyle-colband-size:1; mso-style-priority:99; mso-style-unhide:no; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} table.Tablanormal51FirstRow {mso-style-name:"Tabla normal 51"; mso-table-condition:first-row; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-shading:white; mso-tstyle-shading-themecolor:background1; mso-tstyle-border-bottom:.5pt solid #7F7F7F; mso-tstyle-border-bottom-themecolor:text1; mso-tstyle-border-bottom-themetint:128; font-size:13.0pt; mso-ansi-font-size:13.0pt; mso-bidi-font-size:13.0pt; font-family:"Calibri Light",sans-serif; mso-ascii-font-family:"Calibri Light"; mso-ascii-theme-font:major-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:major-fareast; mso-hansi-font-family:"Calibri Light"; mso-hansi-theme-font:major-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:major-bidi; mso-ansi-font-style:italic; mso-bidi-font-style:italic;} table.Tablanormal51LastRow {mso-style-name:"Tabla normal 51"; mso-table-condition:last-row; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-shading:white; mso-tstyle-shading-themecolor:background1; mso-tstyle-border-top:.5pt solid #7F7F7F; mso-tstyle-border-top-themecolor:text1; mso-tstyle-border-top-themetint:128; font-size:13.0pt; mso-ansi-font-size:13.0pt; mso-bidi-font-size:13.0pt; font-family:"Calibri Light",sans-serif; mso-ascii-font-family:"Calibri Light"; mso-ascii-theme-font:major-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:major-fareast; mso-hansi-font-family:"Calibri Light"; mso-hansi-theme-font:major-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:major-bidi; mso-ansi-font-style:italic; mso-bidi-font-style:italic;} table.Tablanormal51FirstCol {mso-style-name:"Tabla normal 51"; mso-table-condition:first-column; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-shading:white; mso-tstyle-shading-themecolor:background1; mso-tstyle-border-right:.5pt solid #7F7F7F; mso-tstyle-border-right-themecolor:text1; mso-tstyle-border-right-themetint:128; text-align:right; font-size:13.0pt; mso-ansi-font-size:13.0pt; mso-bidi-font-size:13.0pt; font-family:"Calibri Light",sans-serif; mso-ascii-font-family:"Calibri Light"; mso-ascii-theme-font:major-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:major-fareast; mso-hansi-font-family:"Calibri Light"; mso-hansi-theme-font:major-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:major-bidi; mso-ansi-font-style:italic; mso-bidi-font-style:italic;} table.Tablanormal51LastCol {mso-style-name:"Tabla normal 51"; mso-table-condition:last-column; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-shading:white; mso-tstyle-shading-themecolor:background1; mso-tstyle-border-left:.5pt solid #7F7F7F; mso-tstyle-border-left-themecolor:text1; mso-tstyle-border-left-themetint:128; font-size:13.0pt; mso-ansi-font-size:13.0pt; mso-bidi-font-size:13.0pt; font-family:"Calibri Light",sans-serif; mso-ascii-font-family:"Calibri Light"; mso-ascii-theme-font:major-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:major-fareast; mso-hansi-font-family:"Calibri Light"; mso-hansi-theme-font:major-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:major-bidi; mso-ansi-font-style:italic; mso-bidi-font-style:italic;} table.Tablanormal51OddColumn {mso-style-name:"Tabla normal 51"; mso-table-condition:odd-column; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-shading:#F2F2F2; mso-tstyle-shading-themecolor:background1; mso-tstyle-shading-themeshade:242;} table.Tablanormal51OddRow {mso-style-name:"Tabla normal 51"; mso-table-condition:odd-row; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-shading:#F2F2F2; mso-tstyle-shading-themecolor:background1; mso-tstyle-shading-themeshade:242;} table.Tablanormal51NECell {mso-style-name:"Tabla normal 51"; mso-table-condition:ne-cell; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-border-left:cell-none;} table.Tablanormal51NWCell {mso-style-name:"Tabla normal 51"; mso-table-condition:nw-cell; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-border-right:cell-none;} table.Tablanormal51SECell {mso-style-name:"Tabla normal 51"; mso-table-condition:se-cell; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-border-left:cell-none;} table.Tablanormal51SWCell {mso-style-name:"Tabla normal 51"; mso-table-condition:sw-cell; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-border-right:cell-none;} table.Tablanormal21 {mso-style-name:"Tabla normal 21"; mso-tstyle-rowband-size:1; mso-tstyle-colband-size:1; mso-style-priority:99; mso-style-unhide:no; border-top:solid #7F7F7F 1.0pt; mso-border-top-themecolor:text1; mso-border-top-themetint:128; border-left:none; border-bottom:solid #7F7F7F 1.0pt; mso-border-bottom-themecolor:text1; mso-border-bottom-themetint:128; border-right:none; mso-border-top-alt:solid #7F7F7F .5pt; mso-border-top-themecolor:text1; mso-border-top-themetint:128; mso-border-bottom-alt:solid #7F7F7F .5pt; mso-border-bottom-themecolor:text1; mso-border-bottom-themetint:128; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:ES; mso-fareast-language:EN-US;} table.Tablanormal21FirstRow {mso-style-name:"Tabla normal 21"; mso-table-condition:first-row; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-border-bottom:.5pt solid #7F7F7F; mso-tstyle-border-bottom-themecolor:text1; mso-tstyle-border-bottom-themetint:128; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tablanormal21LastRow {mso-style-name:"Tabla normal 21"; mso-table-condition:last-row; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-border-top:.5pt solid #7F7F7F; mso-tstyle-border-top-themecolor:text1; mso-tstyle-border-top-themetint:128; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tablanormal21FirstCol {mso-style-name:"Tabla normal 21"; mso-table-condition:first-column; mso-style-priority:99; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tablanormal21LastCol {mso-style-name:"Tabla normal 21"; mso-table-condition:last-column; mso-style-priority:99; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tablanormal21OddColumn {mso-style-name:"Tabla normal 21"; mso-table-condition:odd-column; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-border-left:.5pt solid #7F7F7F; mso-tstyle-border-left-themecolor:text1; mso-tstyle-border-left-themetint:128; mso-tstyle-border-right:.5pt solid #7F7F7F; mso-tstyle-border-right-themecolor:text1; mso-tstyle-border-right-themetint:128;} table.Tablanormal21EvenColumn {mso-style-name:"Tabla normal 21"; mso-table-condition:even-column; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-border-left:.5pt solid #7F7F7F; mso-tstyle-border-left-themecolor:text1; mso-tstyle-border-left-themetint:128; mso-tstyle-border-right:.5pt solid #7F7F7F; mso-tstyle-border-right-themecolor:text1; mso-tstyle-border-right-themetint:128;} table.Tablanormal21OddRow {mso-style-name:"Tabla normal 21"; mso-table-condition:odd-row; mso-style-priority:99; mso-style-unhide:no; mso-tstyle-border-top:.5pt solid #7F7F7F; mso-tstyle-border-top-themecolor:text1; mso-tstyle-border-top-themetint:128; mso-tstyle-border-bottom:.5pt solid #7F7F7F; mso-tstyle-border-bottom-themecolor:text1; mso-tstyle-border-bottom-themetint:128;} table.Tabladelista6concolores1 {mso-style-name:"Tabla de lista 6 con colores1"; mso-tstyle-rowband-size:1; mso-tstyle-colband-size:1; mso-style-priority:51; mso-style-unhide:no; border-top:solid black 1.0pt; border-left:none; border-bottom:solid black 1.0pt; border-right:none; mso-border-top-alt:solid black .5pt; mso-border-bottom-alt:solid black .5pt; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-fareast-font-family:Calibri; mso-bidi-font-family:"Times New Roman"; color:black; mso-ansi-language:ES; mso-fareast-language:EN-US;} table.Tabladelista6concolores1FirstRow {mso-style-name:"Tabla de lista 6 con colores1"; mso-table-condition:first-row; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-border-bottom:.5pt solid black; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tabladelista6concolores1LastRow {mso-style-name:"Tabla de lista 6 con colores1"; mso-table-condition:last-row; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-border-top:1.5pt double black; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tabladelista6concolores1FirstCol {mso-style-name:"Tabla de lista 6 con colores1"; mso-table-condition:first-column; mso-style-priority:51; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tabladelista6concolores1LastCol {mso-style-name:"Tabla de lista 6 con colores1"; mso-table-condition:last-column; mso-style-priority:51; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tabladelista6concolores1OddColumn {mso-style-name:"Tabla de lista 6 con colores1"; mso-table-condition:odd-column; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-shading:#CCCCCC;} table.Tabladelista6concolores1OddRow {mso-style-name:"Tabla de lista 6 con colores1"; mso-table-condition:odd-row; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-shading:#CCCCCC;} table.Tabladelista6concolores2 {mso-style-name:"Tabla de lista 6 con colores2"; mso-tstyle-rowband-size:1; mso-tstyle-colband-size:1; mso-style-priority:51; mso-style-unhide:no; border-top:solid black 1.0pt; border-left:none; border-bottom:solid black 1.0pt; border-right:none; mso-border-top-alt:solid black .5pt; mso-border-bottom-alt:solid black .5pt; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-fareast-font-family:Calibri; mso-bidi-font-family:"Times New Roman"; color:black; mso-ansi-language:ES; mso-fareast-language:EN-US;} table.Tabladelista6concolores2FirstRow {mso-style-name:"Tabla de lista 6 con colores2"; mso-table-condition:first-row; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-border-bottom:.5pt solid black; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tabladelista6concolores2LastRow {mso-style-name:"Tabla de lista 6 con colores2"; mso-table-condition:last-row; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-border-top:1.5pt double black; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tabladelista6concolores2FirstCol {mso-style-name:"Tabla de lista 6 con colores2"; mso-table-condition:first-column; mso-style-priority:51; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tabladelista6concolores2LastCol {mso-style-name:"Tabla de lista 6 con colores2"; mso-table-condition:last-column; mso-style-priority:51; mso-style-unhide:no; mso-ansi-font-weight:bold; mso-bidi-font-weight:bold;} table.Tabladelista6concolores2OddColumn {mso-style-name:"Tabla de lista 6 con colores2"; mso-table-condition:odd-column; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-shading:#CCCCCC;} table.Tabladelista6concolores2OddRow {mso-style-name:"Tabla de lista 6 con colores2"; mso-table-condition:odd-row; mso-style-priority:51; mso-style-unhide:no; mso-tstyle-shading:#CCCCCC;} </style> <![endif]--><!--[if gte mso 9]><xml> <o:shapedefaults v:ext="edit" spidmax="2053"/> </xml><![endif]--><!--[if gte mso 9]><xml> <o:shapelayout v:ext="edit"> <o:idmap v:ext="edit" data="1"/> </o:shapelayout></xml><![endif]--> </head> <body lang=ES-EC link="#0563C1" vlink="#954F72" style='tab-interval:35.4pt'> <div class=WordSection1> <h1 align=center style='text-align:center'><span style='font-size:20.0pt; font-family:"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-fareast-font-family: "Times New Roman";mso-fareast-theme-font:major-fareast;mso-hansi-theme-font: minor-latin;mso-bidi-font-family:"Times New Roman";mso-bidi-theme-font:major-bidi; mso-font-kerning:0pt;mso-ansi-language:ES-EC;mso-fareast-language:EN-US; mso-bidi-font-weight:normal'>La Virologa y sus grandes acontecimientos</span><a style='mso-footnote-id:ftn1' href="#_ftn1" name="_ftnref1" title=""><sup><span style='font-family:"Calibri",sans-serif;mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman";mso-fareast-theme-font:major-fareast; mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:major-bidi;mso-font-kerning:0pt;mso-ansi-language:ES-EC; mso-fareast-language:EN-US;mso-bidi-font-weight:normal'><span style='mso-special-character: footnote'><![if !supportFootnotes]><b style='mso-bidi-font-weight:normal'><sup><span style='font-size:24.0pt;line-height:105%;font-family:"Calibri",sans-serif; mso-ascii-theme-font:minor-latin;mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:major-fareast;mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman";mso-bidi-theme-font:major-bidi; mso-ansi-language:ES-EC;mso-fareast-language:EN-US;mso-bidi-language:AR-SA'>[1]</span></sup></b><![endif]></span></span></sup></a><sup><span style='font-size:20.0pt;font-family:"Calibri",sans-serif;mso-ascii-theme-font: minor-latin;mso-fareast-font-family:"Times New Roman";mso-fareast-theme-font: major-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:major-bidi;mso-font-kerning:0pt;mso-ansi-language:ES-EC; mso-fareast-language:EN-US;mso-bidi-font-weight:normal'> </span></sup><span style='font-size:20.0pt;font-family:"Calibri",sans-serif;mso-ascii-theme-font: minor-latin;mso-fareast-font-family:"Times New Roman";mso-fareast-theme-font: major-fareast;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:major-bidi;mso-font-kerning:0pt;mso-ansi-language:ES-EC; mso-fareast-language:EN-US;mso-bidi-font-weight:normal'><o:p></o:p></span></h1> <h1 align=center style='text-align:center'><span lang=EN-US style='font-size: 11.0pt;font-family:"Calibri",sans-serif;mso-bidi-font-family:"Times New Roman"; mso-ansi-language:EN-US;font-weight:normal;mso-bidi-font-weight:bold'>The Virology and its great developments<o:p></o:p></span></h1> <p class=ANGLES align=center style='margin:0cm;margin-bottom:.0001pt; text-align:center;line-height:normal'><span style='font-size:11.0pt;font-family: "Calibri",sans-serif;mso-bidi-font-family:"Times New Roman";mso-font-kerning: 18.0pt;mso-ansi-language:ES-EC;mso-fareast-language:ES;mso-bidi-font-weight: bold'>Coello Peralta Roberto<sup>2</sup><o:p></o:p></span></p> <p class=MsoNormal align=center style='margin-top:6.0pt;margin-right:0cm; margin-bottom:6.0pt;margin-left:0cm;text-align:center;line-height:normal; mso-pagination:none;mso-layout-grid-align:none;text-autospace:none'><span lang=ES-TRAD style='font-size:10.0pt;mso-bidi-font-family:Tahoma;color:black; mso-ansi-language:ES-TRAD'>Recibido en septiembre 2018, aceptado en abril 2019</span><span lang=ES-TRAD style='font-size:10.0pt;mso-bidi-font-family:Times;color:black; mso-ansi-language:ES-TRAD'><o:p></o:p></span></p> <p class=MsoNoSpacing style='margin-top:6.0pt;margin-right:0cm;margin-bottom: 6.0pt;margin-left:0cm;text-align:justify'><span lang=ES-TRAD style='mso-fareast-font-family: "Times New Roman";mso-ansi-language:ES-TRAD'><o:p>&nbsp;</o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;line-height:normal'><b style='mso-bidi-font-weight:normal'><span lang=ES style='font-size:10.0pt;mso-bidi-font-size:12.0pt;mso-fareast-font-family: "Times New Roman";mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin; mso-fareast-language:ES'>RESUMEN<o:p></o:p></span></b></p> <p class=MsoNormal style='text-align:justify;line-height:normal'><span lang=EN-US style='mso-ansi-language:EN-US'>El presente es una revisin bibliogrfica, acerca de grandes acontecimientos surgidos durante el estudio de los virus, desde la antigedad hasta los actuales das. As mismo, es de notable relevancia mencionar que el dinamismo de los virus y la aparicin de nuevas metodologas de diagnsticos e innovaciones, han conllevado al surgimiento y resurgimiento de esta disciplina, de importancia en Agricultura, Vida Silvestre, Sanidad Animal, Salud Pblica, entre otras.<o:p></o:p></span></p> <p class=ANGLES style='margin-top:6.0pt;line-height:normal'><b style='mso-bidi-font-weight:normal'><span lang=X-NONE style='font-size:11.0pt; font-family:"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-hansi-theme-font: minor-latin;mso-bidi-theme-font:minor-latin;mso-fareast-language:ES'>Palabras clave<i style='mso-bidi-font-style:normal'>:</i></span></b><b style='mso-bidi-font-weight: normal'><i style='mso-bidi-font-style:normal'><span lang=X-NONE style='font-size:11.0pt;font-family:"Calibri",sans-serif;mso-ascii-theme-font: minor-latin;mso-hansi-theme-font:minor-latin;mso-bidi-theme-font:minor-latin; mso-ansi-language:ES;mso-fareast-language:ES'> </span></i></b><span style='font-size:11.0pt;font-family:"Calibri",sans-serif;mso-ascii-theme-font: minor-latin;mso-fareast-font-family:Calibri;mso-fareast-theme-font:minor-latin; mso-hansi-theme-font:minor-latin;mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;mso-ansi-language:ES-EC;mso-fareast-language: EN-US'>Virologa, Virus, cientficos, acontecimientos. </span><b style='mso-bidi-font-weight:normal'><span lang=X-NONE style='mso-bidi-font-size: 12.0pt;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;mso-fareast-language: ES'><o:p></o:p></span></b></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;line-height:normal'><b style='mso-bidi-font-weight:normal'><span lang=EN-US style='font-size:10.0pt;mso-bidi-font-size:12.0pt;mso-fareast-font-family: "Times New Roman";mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin; mso-ansi-language:EN-US;mso-fareast-language:ES'>ABSTRACT<o:p></o:p></span></b></p> <p class=MsoNormal style='text-align:justify;line-height:normal'><span lang=EN-US style='mso-ansi-language:EN-US'>This is a bibliographic review, about major events that have arisen during the study of viruses, from ancient times to the present days. Likewise, it is of remarkable relevance to mention that the dynamism of the viruses and the appearance of new methodologies of diagnoses and innovations, have led to the emergence and resurgence of this discipline, of importance in Agriculture, Wildlife, Animal Health, Public Health, among others<o:p></o:p></span></p> <p class=MsoNormal style='margin-bottom:0cm;margin-bottom:.0001pt;line-height: normal;mso-outline-level:1'><b style='mso-bidi-font-weight:normal'><span lang=EN-US style='mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin; mso-ansi-language:EN-US'>Key words<i style='mso-bidi-font-style:normal'>: </i></span></b><span class=tlid-translation><span lang=EN style='mso-ansi-language:EN'>Virology, Viruses, scientists, events</span><span lang=EN> </span><span lang=ES><o:p></o:p></span></span></p> <p class=MsoNormal style='margin-bottom:0cm;margin-bottom:.0001pt;line-height: normal;mso-outline-level:1'><span class=tlid-translation><span lang=ES><o:p>&nbsp;</o:p></span></span></p> <p class=MsoNormal style='margin-bottom:0cm;margin-bottom:.0001pt;line-height: normal;mso-outline-level:1'><span class=tlid-translation><span lang=ES><o:p>&nbsp;</o:p></span></span></p> <p class=ANGLES style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:36.0pt;text-indent:-18.0pt;line-height:150%;mso-list:l1 level1 lfo2'><![if !supportLists]><b style='mso-bidi-font-weight:normal'><span lang=X-NONE style='font-size:16.0pt; mso-bidi-font-size:12.0pt;line-height:150%;mso-fareast-font-family:Arial; mso-bidi-font-family:Arial;mso-fareast-language:ES'><span style='mso-list:Ignore'>1.<span style='font:7.0pt "Times New Roman"'>&nbsp;&nbsp; </span></span></span></b><![endif]><b style='mso-bidi-font-weight:normal'><span lang=X-NONE style='font-size:16.0pt; mso-bidi-font-size:12.0pt;line-height:150%;font-family:"Calibri",sans-serif; mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;mso-bidi-theme-font: minor-latin;mso-fareast-language:ES'>Introduccin</span></b><b style='mso-bidi-font-weight:normal'><span lang=X-NONE style='font-size:16.0pt; mso-bidi-font-size:12.0pt;line-height:150%;mso-bidi-font-family:Calibri; mso-bidi-theme-font:minor-latin;mso-fareast-language:ES'><o:p></o:p></span></b></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>La Virologa es una ciencia rama de la biologa que se encarga del estudio de los virus, los mismos que son capaces de infectar al hombre, animales, plantas e incluso bacterias y hongos. As mismo, actualmente existen evidencias que los virus pueden infectar virus, a los que se definen como <span class=SpellE>Virfagos</span> (<span class=SpellE><a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Bekliz%20M%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=27886075"><span style='color:windowtext;text-decoration:none;text-underline:none'>Bekliz</span></a></span>, <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Colson%20P%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=27886075"><span class=SpellE><span style='color:windowtext;text-decoration:none;text-underline: none'>Colson</span></span></a>, &amp;&nbsp;<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=La%20Scola%20B%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=27886075"><span style='color:windowtext;text-decoration:none;text-underline:none'>La <span class=SpellE>Scola</span></span></a>, 2016, pg. 317).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Etimolgicamente, virus significa veneno en latn, segn <span class=SpellE>Carballal</span> y <span class=SpellE>Oubia</span> (2015), definen al virus como un programa, o un complejo informacional macromolecular.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Segn algunos virlogos, definen a los virus de acuerdo a las siguientes caractersticas:<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Son agentes infecciosos <span class=SpellE>submicroscpicos</span> (Adamo et al, 2014, pg. 15-30).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Heterogneos, varan en tamao, morfologa, composicin qumica, rango de hospedadores, entre otros (Wagner, Martnez, Bloom, &amp; <span class=SpellE>Camerini</span>, 2011, pg. 1-533).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Potencialmente patgenos. <o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Carecen de los sistemas enzimticos productores de energa necesaria para la sntesis de cidos nucleicos y de protenas.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Parsitos genticos obligados intracelulares. <o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Posee un solo tipo de cido nucleico (ADN o ARN).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Carece de organizacin celular (no posee ribosomas, no mitocondrias, <span class=SpellE>etc</span>). <o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Y se replican por copia de su material gentico (<span class=SpellE>MacLachlan</span> &amp; <span class=SpellE>Dubovi</span>, 2016, pg. 59; <span class=SpellE>Carballal</span> &amp; <span class=SpellE>Oubia</span>, 2015, pg. 7-90).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'><o:p>&nbsp;</o:p></span></p> <p class=MsoNormal align=center style='margin-top:6.0pt;margin-right:0cm; margin-bottom:6.0pt;margin-left:0cm;text-align:center;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family: Arial;mso-no-proof:yes'><!--[if gte vml 1]><v:shapetype id="_x0000_t75" coordsize="21600,21600" o:spt="75" o:preferrelative="t" path="m@4@5l@4@11@9@11@9@5xe" filled="f" stroked="f"> <v:stroke joinstyle="miter"/> <v:formulas> <v:f eqn="if lineDrawn pixelLineWidth 0"/> <v:f eqn="sum @0 1 0"/> <v:f eqn="sum 0 0 @1"/> <v:f eqn="prod @2 1 2"/> <v:f eqn="prod @3 21600 pixelWidth"/> <v:f eqn="prod @3 21600 pixelHeight"/> <v:f eqn="sum @0 0 1"/> <v:f eqn="prod @6 1 2"/> <v:f eqn="prod @7 21600 pixelWidth"/> <v:f eqn="sum @8 21600 0"/> <v:f eqn="prod @7 21600 pixelHeight"/> <v:f eqn="sum @10 21600 0"/> </v:formulas> <v:path o:extrusionok="f" gradientshapeok="t" o:connecttype="rect"/> <o:lock v:ext="edit" aspectratio="t"/> </v:shapetype><v:shape id="Imagen_x0020_7" o:spid="_x0000_i1026" type="#_x0000_t75" alt="Saint Louis encephalitis virus NS1" style='width:150pt;height:150pt; visibility:visible;mso-wrap-style:square'> <v:imagedata src="listo.fld/image003.jpg" o:title="Saint Louis encephalitis virus NS1"/> </v:shape><![endif]--><![if !vml]><img border=0 width=150 height=150 src="listo.fld/image003.jpg" alt="Saint Louis encephalitis virus NS1" v:shapes="Imagen_x0020_7"><![endif]></span><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family: Arial'><o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>TOMADO DE: <a href="https://thenativeantigencompany.com/products/west-nile-virus-ns1-protein/"><span style='color:windowtext;text-decoration:none;text-underline:none'>https://thenativeantigencompany.com/products/west-nile-virus-ns1-protein/</span></a> <o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>El presente describe cmo cientficos/investigadores han contribuido al estudio de esta importante disciplina.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Cronologa Histrica:<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Aunque no existen registros de las epidemias producidas por los virus en las pocas antiguas y medievales, muchas de estas enfermedades eran conocidas por las civilizaciones greco latinas. Sin embargo, existen evidencias arqueolgicas en momias del antiguo Egipto y en antiguos grabados, que datan de 3000 aos a.C., en donde muestran lesiones caractersticas de viruela y poliomielitis. <o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Enfermedades como la rabia, influenza y poliomielitis tambin fueron conocidas por las antiguas civilizaciones (<span class=SpellE>Carballal</span> &amp; <span class=SpellE>Oubia</span>, 2015, pg. 7-90).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Transcurri el tiempo, hasta que en 1673 el holands Anthony Van <span class=SpellE>Leuewenhoek</span> invent el microscopio y as observ microbios (<span class=SpellE>Procop</span>, 2017, pg. 1951-1956).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Luego, en 1789 Eduardo <span class=SpellE>Jenner</span>, Considerado el padre de la Inmunologa, inocul costras con el virus de vaccnea a un nio de 8 aos y describe de esta forma el primer mtodo inmunolgico denominado vacunacin (Abbas, <span class=SpellE>Lichtman</span>, &amp; <span class=SpellE>Pillai</span>, 2016, pg. 312).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Despus, para 1864 - Lus Pasteur refuta la teora de la  generacin espontnea y demuestra que las enfermedades infecciosas resultaban de la infeccin con microorganismos.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Diecisis aos despus, Robert Koch, enuncia sus  Postulados que constituye el fundamento de la asignacin etiolgica de las enfermedades infecciosas. (<span class=SpellE>Procop</span>, 2017, pg. 1951-1956)<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>A continuacin, en 1884 - Luis Pasteur, pas el virus de la rabia por conejos y desarrollo la vacuna antirrbica, un gran acontecimiento para esa poca (<span class=SpellE>Shors</span>, 2010, pg. 1-622).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Algo muy importante, se dio en 1886, cuando Charles Chamberlain desarroll un filtro de porcelana que permita retener las bacterias, pero no a otras sustancias o agentes ms pequeos que podran atravesar dichos filtros. (<span class=SpellE>Procop</span>, 2017, pg. 1951-1956).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Subsiguientemente, se present un acontecimiento importante en 1892, cuando Dimitri <span class=SpellE>Ivanowsky</span>, considerado el padre de la VIROLOGIA, investigando sobre la enfermedad del mosaico del tabaco (utilizando los filtros de Chamberlain), observ que de un extracto obtenido de la maceracin de hojas infectadas era capaz de transmitir la enfermedad; este investigador atribuy a las toxinas producida por las bacterias que podran atravesar filtros, a lo que se refiri a fluidos infectantes, pero ms tarde se conoci que esta infeccin se deba al virus del mosaico del tabaco. A <span class=SpellE>Ivanowsky</span> se lo considera el padre de la Virologa.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Entre 1897  1898, Friedrich <span class=SpellE>Loeffler</span> y Pal <span class=SpellE>Frosch</span> descubren el virus con afectacin animal, llamado virus de la fiebre aftosa (<span class=SpellE>MacLachlan</span> &amp; <span class=SpellE>Dubovi</span>, 2016, pg. 59).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Tambin un hecho importante se llev acabo en 1898, cuando <span class=SpellE>Martinus</span> <span class=SpellE>Beijernick</span>, muele las hojas de plantas enfermas, lo pasa por filtros de membrana y el contenido de la filtracin lo infecta en plantas sanas, describe el termino de Virus filtrable y habla del contagio in vivo de un virus vegetal (Virus del Mosaico del Tabaco). (<span class=SpellE>Procop</span>, 2017, pg. 1951-1956).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Cuatro aos despus, Walter Reed Realiz importantes investigaciones sobre: la&nbsp;<a href="https://www.ecured.cu/Etiolog%C3%ADa" title=Etiologa><span style='color:windowtext;text-decoration:none;text-underline:none'>etiologa</span></a>, control y transmisin de la Fiebre amarilla.<span style='mso-spacerun:yes'> </span><o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Otro acontecimiento destacable se dio en 1908, cuando <span class=SpellE>Landteiner</span> y Popper, transmiten el virus polio del hombre al mono (<span class=SpellE>transmision</span> experimental), siendo uno de los sistemas biolgicos para replicar virus en el laboratorio (<span class=SpellE>Shors</span>, 2010, pg. 1-622). <o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>En el mismo ao <span class=SpellE>Ellerman</span> y <span class=SpellE>Bang</span> descubren virus en leucemias de pollo, luego en 1911 <span class=SpellE>Francys</span> <span class=SpellE>Peyton</span> <span class=SpellE>Rous</span>, utiliza por primera vez embrin de pollo, que es otro sistema <span class=SpellE>biologco</span> para replicar virus en el laboratorio, describiendo de esta forma el virus del sarcoma de <span class=SpellE>Rous</span> y en 1966 este ltimo, recibe el premio nobel por el descubrimiento de virus tumorales (<span class=SpellE>Cabasso</span>, 1967, pg. 51-57; <span class=SpellE>MacLachlan</span> &amp; <span class=SpellE>Dubovi</span>, 2016, pg. 59).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Luego, Frederick <span class=SpellE>Twort</span>, un <span class=SpellE>bacteriologo</span> <span class=SpellE>britanico</span> en 1915 accidentalmente observ el efecto de ciertos filtrados sobre las bacterias y dos aos ms tarde en 1917, <span class=SpellE>Felix</span> <span class=SpellE>D Herelle</span> describi que estos infiltrados atacaban bacterias y los denomin bacterifagos; ambos descubrieron los <span class=SpellE>bacteriofagos</span> (<span class=SpellE>MacLachlan</span> &amp; <span class=SpellE>Dubovi</span>, 2016, pg. 59).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>A continuacin, entre 1925 a 1930, <a href="https://es.wikipedia.org/wiki/Ernst_Ruska" title="Ernst Ruska"><span style='color:windowtext;text-decoration:none;text-underline:none'>Ernst <span class=SpellE>Ruska</span></span></a>&nbsp;y&nbsp;<a href="https://es.wikipedia.org/wiki/Max_Knoll"><span style='color:windowtext; text-decoration:none;text-underline:none'>Max <span class=SpellE>Knoll</span></span></a> construyen el microscopio electrnico, el mismo que permite una&nbsp;amplificacin de ms de 1200 veces el tamao de muestra original (<span class=SpellE>Amano</span> &amp; Daz, 2015, pg. 15-30).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Subsiguientemente, utilizando el microscopio electrnico, <span class=SpellE>Wendell</span> Stanley en 1935 (Premio nobel) realiz el aislamiento, purificacin y cristalizacin del virus del mosaico del tabaco (<span class=SpellE>Tabamovirus</span>) (Le, 1986, pg. 450-472).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>As mismo, en este ltimo ao, Max <span class=SpellE>Theiler</span> y Smith, (Premios nobel) <span class=SpellE>obtuveron</span> la vacuna contra el virus de la fiebre amarilla (<span class=SpellE>Theiler</span>&nbsp;<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Smith%20HH%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=19870634"><span style='color:windowtext;text-decoration:none;text-underline:none'>&amp; Smith,</span></a> 1937, pg. 787-800).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Un ao despus<a href="https://www.cdc.gov/vaccines/pubs/pinkbook/flu.html"><span style='color:windowtext;text-decoration:none;text-underline:none'>, <span class=SpellE>Burnet</span> descubre que se puede replicar el virus de influenza en embriones de huevos de gallinas.</span></a> (CDC, 2019, pg. 1-3). Y en 1940 G. K. <span class=SpellE>Hirst</span>, descubri que el virus de influenza se aglutina alrededor de los <span class=SpellE>globulos</span> rojos, lo que se conoce como Hemaglutinacin (Lpez, 1963, pg. 945-951).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>En 1943 <span class=SpellE>Huang</span> descubri cambios necrticos (efectos <span class=SpellE>citopticos</span>) en clulas embrionarias de pollo, inoculados con el virus de encefalitis equina.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Pero otro hecho trascendental en la historia de la virologa, se dio en 1949, cuando John F. <span class=SpellE>Enders</span>, Thomas <span class=SpellE>Weller</span> y Frederick <span class=SpellE>Robbins</span> (Premios nobel) describieron el cultivo del virus de la poliomielitis, posteriormente entre 1950 a 1960 muchos otros virus se cultivaron utilizando los mismos principios, lo que dio origen al tercer sistema biolgico de replicacin viral que son los cultivos celulares.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Entre 1952-1955 ante la presencia de la Pandemia de la Poliomielitis, <span class=SpellE>Jonas</span> <span class=SpellE>Salk</span>, logr obtener la primera vacuna contra la Poliomielitis (intramuscular), a travs de virus inactivados o muertos. Luego en 1957- Albert <span class=SpellE>Seivin</span>, obtuvo la segunda Vacuna contra la <span class=SpellE>Poliomietitis</span> (oral) obtenida de virus vivo (atenuados).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Despus, en 1956, Watson y Crick (1956) realizaron descubrimientos concernientes a la estructura molecular de los cidos desoxirribonucleicos (ADN) y su importancia para la transferencia de informacin en la materia viva (Leonard et al, 1986, pg. 255-265).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>En 1959 <span class=SpellE>Brenner</span> y <span class=SpellE>Horne</span> desarrollaron la tincin negativa, con la cual se podra diferenciar las estructuras internas de los virus (<span class=SpellE><a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=BRENNER%20S%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=13804200"><span style='color:windowtext;text-decoration:none;text-underline:none'>Brenner</span></a></span>&nbsp;&amp; <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=HORNE%20RW%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=13804200"><span class=SpellE><span style='color:windowtext;text-decoration:none;text-underline: none'>Horne</span></span><span style='color:windowtext;text-decoration:none; text-underline:none'>,</span></a> 1959, pg. 103-110).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Por otro lado, en 1962 - &nbsp;<a href="https://es.wikipedia.org/wiki/Howard_Temin" title="Howard Temin"><span style='color:windowtext;text-decoration:none; text-underline:none'>Howard <span class=SpellE>Temin</span></span></a>&nbsp;y&nbsp;<a href="https://es.wikipedia.org/wiki/David_Baltimore"><span style='color:windowtext; text-decoration:none;text-underline:none'>David Baltimore</span></a>, describieron la transcripcin inversa, la misma que contradice el&nbsp;<a href="https://es.wikipedia.org/wiki/Dogma_central_de_la_biolog%C3%ADa_molecular" title="Dogma central de la biologa molecular"><span style='color:windowtext; text-decoration:none;text-underline:none'>dogma central de la biologa molecular</span></a>, que establece que el ADN se transcribe en ARN. En ese mismo ao, Los investigadores <span class=SpellE>Francois</span> Jacob, Andr <span class=SpellE>Lwoff</span> y Jacques <span class=SpellE>Monod</span> (premios nobel) realizan la descripcin de <span class=SpellE>operones</span> y <span class=SpellE>bacteriofagos</span>; as mismo en MARBURGO (Alemania), se describe el Virus del <span class=SpellE>marburgo</span> causante de fiebres hemorrgicas con alta tasa de mortalidad en humanos.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Luego, en 1966 en <span class=SpellE>Moscu</span> se establece el Comit Internacional de Nomenclatura de los virus, que es el rgano que autoriza y organiza la clasificacin&nbsp;<a href="https://es.wikipedia.org/wiki/Taxonom%C3%ADa" title=Taxonoma><span style='color:windowtext;text-decoration:none;text-underline: none'>taxonmica</span></a>&nbsp;de los&nbsp;<a href="https://es.wikipedia.org/wiki/Virus" title=Virus><span style='color:windowtext; text-decoration:none;text-underline:none'>virus</span></a> (ICTV, 2018, pg. 5-13).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Despus, en 1969 Max <span class=SpellE>Delbruck</span>, Alfred <span class=SpellE>Hersey</span> y Salvador Luria, (premios nobel) describieron el mecanismo de infeccin de los <span class=SpellE>bacteriofagos</span> en clulas.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Otro hecho importante en la virologa, fue cuando David Baltimore, Howard <span class=SpellE>Temin</span> y Renato <span class=SpellE>Dulbeco</span> (premios nobel) en 1975 realizaron el descubrimiento de la interaccin entre los virus tumorales (<span class=SpellE>Retroviridae</span>) y el genoma celular (<span class=SpellE>Shors</span>, 2010, pg. 1-622).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>En 1976 aparece el Virus del <span class=SpellE>ebola</span>, en dos brotes simultneos ocurridos en <span class=SpellE>Nzara</span> (hoy Sudn del Sur) y <span class=SpellE>Yambuku</span> (Repblica Democrtica del Congo), la aldea en que se produjo el segundo de ellos est situada cerca del ro <span class=SpellE>Ebola</span>, que da nombre al virus, el mismo, que cuenta con una taza de mortalidad del 90% (OMS, 2018, pg. 1-3). As mismo, en el mismo ao D. <span class=SpellE>Carleton</span> <span class=SpellE>Gajdusek</span> y Baruch <span class=SpellE>Blumberg</span> (premios nobel) descubrieron los priones y los <span class=SpellE>Hepadniviridae</span>, respectivamente (<span class=SpellE>Shors</span>, 2010, pg. 1-622).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Por otro lado, en 1977-Roberto Gallo, Descubre los virus leucmicos, HTLV1 Y HTLV2 (Virus <span class=SpellE>linfotropicos</span> Humanos) y es considerado el padre de los Retrovirus.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>En 1978, Daniel <span class=SpellE>Nathans</span> (premio nobel) describi el uso de las enzimas de restriccin en el estudio de la gentica del virus SV-40 (<span class=SpellE>Poliomaviridae</span>).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Dos aos siguientes, el premio nobel Pal <span class=SpellE>Berg</span> en 1980 realiz la recombinacin de cidos nucleicos e insercin de genes (<span class=SpellE>Poliomaviridae</span>) y en 1986 se produce las primeras vacunas por <span class=SpellE>ingenieria</span> gentica, que es la vacuna contra el virus de la hepatitis B (<span class=SpellE>Shors</span>, 2010, <span class=GramE>pg. ;</span> R&amp;D <span class=SpellE>Systems</span>, 2018, pg. 1-3).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>As mismo, a comienzo de los 80 apareci un virus pandmico desconocido, que en 1984 el Dr. Roberto Gallo lo public como HTLV 3, y posteriormente el equipo de <span class=SpellE>Luc</span> <span class=SpellE>Montanier</span> lo describi como virus LAV (virus asociado a <span class=SpellE>linfoadenopatia</span> generalizada). Ante esta controversia, en 1986 un comit de expertos lo denominaron virus del VIH, causante del SIDA (<span class=SpellE>Shors</span>, 2010, pg. 1-622).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>En 1982 <span class=SpellE>Aaron</span> <span class=SpellE>Klung</span> (premio nobel) efectu la determinacin de la estructura de complejos de cidos nucleicos y protenas por cristalografa y microscopa electrnica. (<span class=SpellE>Tobamovirus</span> y <span class=SpellE>Tymmovirus</span>).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Por otro lado, los cientficos George <span class=SpellE>Hitching</span> y <span class=SpellE>Gertrude</span> <span class=SpellE>Elion</span> (premios nobel) en 1988, realiz los principios del desarrollo de antivirales (<span class=SpellE>aciclovir</span>).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Un ao despus en 1989 Michael <span class=SpellE>Bishop</span> y Harold <span class=SpellE>Varnus</span> (premios nobel), realiz el descubrimiento del origen celular de los oncogenes (<span class=SpellE>Retroviridae</span>).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Posteriormente, en 1984 se desarrollaron los anticuerpos monoclonales por <a href="https://es.wikipedia.org/wiki/Niels_K._Jerne" title="Niels K. Jerne"><span style='color:windowtext;text-decoration:none;text-underline:none'>Niels K. <span class=SpellE>Jerne</span></span></a>,&nbsp;<a href="https://es.wikipedia.org/wiki/Georges_K%C3%B6hler"><span style='color:windowtext;text-decoration:none;text-underline:none'>Georges <span class=SpellE>Khler</span></span></a>&nbsp;y&nbsp;<a href="https://es.wikipedia.org/wiki/Cesar_Milstein" title="Cesar Milstein"><span style='color:windowtext;text-decoration:none;text-underline:none'>Cesar <span class=SpellE>Milstein</span></span></a>, los mismos que se utilizan para tratamiento y diagnstico de diversas enfermedades.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>A continuacin, en 1993, <span class=SpellE>Phill</span> Sharp y Richards Roberts (premios nobel) descubrieron la discontinuidad de los genes (<span class=SpellE>Splicing</span>) utilizando un Adenovirus causante del resfriado.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Para 1996, <span class=SpellE>Rolf</span> <span class=SpellE>Zinkernagel</span> y Peter <span class=SpellE>Doherty</span> (Premios nobel) describieron la presentacin de los antgenos virales a los sistemas mayores de histocompatibilidad. </span><span lang=EN-US style='mso-bidi-font-size:10.0pt; line-height:150%;mso-bidi-font-family:Arial;mso-ansi-language:EN-US'>(<span class=SpellE>Shors</span>, 2010, <span class=SpellE>pg</span>. 1-622; <span class=SpellE>Carballal</span> G., &amp; <span class=SpellE>Oubia</span>, 2015, <span class=SpellE>pg</span>. 7-90; R&amp;D Systems, 2018, pg.1-3)<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Despus, Stanley <span class=SpellE>Prusiener</span> (premio nobel) en 1999, realiz la caracterizacin de los priones; en el mismo ao apareci por primera vez el Virus del Nilo Occidental en New York (EEUU), donde produjo muchas epizootias y epidemias (<span class=SpellE>Enquist</span>, 2009, <span class=GramE>pg. ;</span> R&amp;D <span class=SpellE>Systems</span>, 2018, pg. 1-3).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Por otro lado, desde el ao 2000 en adelante se presentaron, <span class=GramE>varios acontecimientos entre ellos se destaca</span>: En el 2003 el Centro de Control y Prevencin de Enfermedades (CDC) y el laboratorio de Microbiologa del hospital Nacional de <span class=SpellE>Canada</span> identificaros el virus causarte del <span class=SpellE>sindrome</span> agudo respiratorio severo (SARS). Luego en el 2006 se crean las vacunas contra el Rotavirus y el Virus del Papiloma Humano (<span class=SpellE>Enquist</span>, 2009, pg. 5296-5308; R&amp;D <span class=SpellE>Systems</span>, 2018, pg. 1-3).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Para el 2008 se descubrieron virus que infectan virus gigantes en las mismas clulas eucariotas, a los que se denominaron, <span class=SpellE>Virofagos</span>, que miden de 35 a 74 nanmetros (<span class=SpellE>nm</span>), poseen <span class=SpellE>cpsides</span> con simetra <span class=SpellE>icosadrica</span> y genomas de ADN <span class=SpellE>bicatenario</span> grandes de 17 a 29 <span class=SpellE>kilopares</span> de bases (<span class=SpellE>kbp</span>) con 16 a 34 genes (<span class=SpellE>Bekliz</span>, 2016, pg. 317).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Otro acontecimiento, fue el que aconteci en el 2009 donde se apareci la pandemia mundial llamada influenza porcina, causada por el virus de influenza A H1N1, este virus posea genes aviar, del cerdo y humano. El virus salto la barrera de especies, <span class=SpellE>transmitiendose</span> de los animales a humanos; luego el virus se extendi de humano a humano por el <span class=GramE>mundo<span style='mso-spacerun:yes'> </span>(</span><span class=SpellE>Enquist</span>, 2009, pg. 5296-5308; R&amp;D <span class=SpellE>Systems</span>, 2018, pg. 1-3).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Para el 2011, la Organizacin Mundial de Sanidad (OMS) declar oficialmente libre de peste bovina, luego en el 2012 se detect el coronavirus causante del sndrome respiratorio del Medio Oriente (MERS) con posible transmisin de camellos a humanos.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Por otro lado, en la Regin de las Amricas en diciembre de 2013, se detect por primera vez la transmisin autctona del virus <span class=SpellE>Chikungunya</span>. A partir de esa fecha y hasta el 30 de mayo del 2014, la Organizacin Panamericana de la Salud (OPS) notificaron 4,406 casos confirmados en 18 pases.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Otro hecho se dio, entre 2014 al 2016, donde apareci el mayor&nbsp;<a href="https://es.wikipedia.org/wiki/Brote_epid%C3%A9mico" title="Brote epidmico"><span style='color:windowtext;text-decoration:none; text-underline:none'>brote epidmico</span></a>&nbsp;de la&nbsp;<a href="https://es.wikipedia.org/wiki/Enfermedad_por_el_virus_del_%C3%89bola" title="Enfermedad por el virus del bola"><span style='color:windowtext; text-decoration:none;text-underline:none'>enfermedad por el virus del <span class=SpellE>bola</span></span></a>, y extendido posteriormente a&nbsp;<a href="https://es.wikipedia.org/wiki/Liberia" title=Liberia><span style='color:windowtext;text-decoration:none;text-underline:none'>Liberia</span></a>,&nbsp;<a href="https://es.wikipedia.org/wiki/Sierra_Leona" title="Sierra Leona"><span style='color:windowtext;text-decoration:none;text-underline:none'>Sierra Leona</span></a>,&nbsp;<a href="https://es.wikipedia.org/wiki/Nigeria" title=Nigeria><span style='color:windowtext;text-decoration:none;text-underline:none'>Nigeria</span></a>,&nbsp;<a href="https://es.wikipedia.org/wiki/Senegal" title=Senegal><span style='color:windowtext;text-decoration:none;text-underline:none'>Senegal</span></a>,&nbsp;<a href="https://es.wikipedia.org/wiki/Estados_Unidos" title="Estados Unidos"><span style='color:windowtext;text-decoration:none;text-underline:none'>Estados Unidos</span></a>,&nbsp;<a href="https://es.wikipedia.org/wiki/Espa%C3%B1a" title=Espaa><span style='color:windowtext;text-decoration:none;text-underline: none'>Espaa</span></a>,&nbsp;<a href="https://es.wikipedia.org/wiki/Mal%C3%AD" title=Mal><span style='color:windowtext;text-decoration:none;text-underline: none'>Mal</span></a>&nbsp;y&nbsp;<a href="https://es.wikipedia.org/wiki/Reino_Unido" title="Reino Unido"><span style='color:windowtext;text-decoration:none;text-underline:none'>Reino Unido</span></a>.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Despus, entre 2015 y 2016 apareci en Brasil el virus <span class=SpellE>Zika</span> y luego se disemin por muchos pases alcanzando niveles pandmicos (<span class=SpellE>Enquist</span>, 2009, pg. 5296-5308; R&amp;D <span class=SpellE>Systems</span>, 2018, pg. 1-3).<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><span lang=ES style='mso-bidi-font-size:10.0pt;line-height:150%;mso-bidi-font-family:Arial'>Finalmente, es importante mencionar que ante los notables progresos cientficos en el mundo (diagnstico, prevencin y otros), los virus siguen desafiando al mundo, con aparicin de virus antiguos (reemergentes) y nuevas virosis (emergentes), por lo consiguiente, es notable su estudio y seguir evolucionando en <span class=SpellE>metodologias</span> diagnsticas y de control y prevencin.<o:p></o:p></span></p> <p class=MsoNormal style='margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;line-height:150%'><b style='mso-bidi-font-weight: normal'><span lang=ES style='font-size:16.0pt;mso-bidi-font-size:11.0pt; line-height:150%;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin'>Referencias bibliogrficas<o:p></o:p></span></b></p> <w:Sdt Bibliography="t" ID="111145805"> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>Abbas, A., Lichtman, A., &amp; Pillai, S. (2016). Inmunologa celular y molecular. Octava edicin. En Libro de Inmunologa (pg. 312). Barcelona-Espaa: ELSEVIER. <o:p></o:p></span></i><span lang=ES><w:sdtPr></w:sdtPr></span></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>Adamo, M. et al. (2014). Virologa Mdica In Vivo. Primera edicin. En Libro de Virologa (pg. 434- 436). Crdoba-Argentina: BRUJAS <o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>Amano, Y. J., &amp; Daz, L. (2015). Introduccin a la Microscopa Electrnica: Principios-Aplicaciones. Tercera edicin. En Libro de Microscopa Electrnica (pg. 15-30). Guayaquil-Ecuador: INSPI.<o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'><a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Bekliz%20M%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=27886075"><span style='color:windowtext;text-decoration:none;text-underline:none'>Bekliz</span></a>, M.,&nbsp;<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Colson%20P%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=27886075"><span style='color:windowtext;text-decoration:none;text-underline:none'>Colson</span></a>, P., &amp;&nbsp;<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=La%20Scola%20B%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=27886075"><span style='color:windowtext;text-decoration:none;text-underline:none'>La Scola</span></a>, B. (2016). </span></i><i><span lang=EN-US style='mso-ansi-language:EN-US; mso-no-proof:yes'>The Expanding Family of Virophages. En Artculo cientfico de Rev. Viruses, 8 (11). (pg. 317).<o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'><a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=BRENNER%20S%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=13804200"><span lang=EN-US style='color:windowtext;mso-ansi-language:EN-US;text-decoration: none;text-underline:none'>Brenner, S</span></a></span></i><i><span lang=EN-US style='mso-ansi-language:EN-US;mso-no-proof:yes'>.,&nbsp;&amp; </span></i><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'><a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=HORNE%20RW%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=13804200"><span lang=EN-US style='color:windowtext;mso-ansi-language:EN-US;text-decoration: none;text-underline:none'>Horne, R. W</span></a></span></i><i><span lang=EN-US style='mso-ansi-language:EN-US;mso-no-proof:yes'>. (1959). A negative staining method for high resolution electron microscopy of viruses. </span></i><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>En Artculo cientfico de Rev. <a href="https://www.ncbi.nlm.nih.gov/pubmed/13804200" title="Biochimica et biophysica acta."><span style='color:windowtext; text-decoration:none;text-underline:none'>Biochim Biophys Acta</span></a>, 34(1). (pg. 103-110).<o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>Cabasso, V. (1967). Algunos progresos en Virologa. En Artculo cientfico de la Academia Nacional de Agronoma y Veterinaria. Buenos Aires-Argentina, 6 (1). (pg. 51-57). Recuperado de: <a href="http://sedici.unlp.edu.ar/bitstream/handle/10915/32903/Documento_completo.pdf?sequence=1&amp;isAllowed=y"><span style='color:windowtext;text-decoration:none;text-underline:none'>http://sedici.unlp.edu.ar/bitstream/handle/10915/32903/Documento_completo.pdf?sequence=1&amp;isAllowed=y</span></a><o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>Carballal, G., &amp; Oubia, J. (2015). Virologa Mdica. Cuarta edicin. (pg. 7-90). Buenos Aires-Argentina: CORPUS.<o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>Centro para el Control y la Prevencin de Enfermedades (CDC). (2019). Influenza (gripe). Cronologa histrica de la Influenza. En lnea, (pg. 1-3). Recuperado de: <a href="https://espanol.cdc.gov/enes/flu/pandemic-resources/pandemic-timeline-1930-and-beyond.htm"><span style='color:windowtext;text-decoration:none;text-underline:none'>https://espanol.cdc.gov/enes/flu/pandemic-resources/pandemic-timeline-1930-and-beyond.htm</span></a><o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'><a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Enquist%20LW%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=19297504"><span lang=EN-US style='color:windowtext;mso-ansi-language:EN-US;text-decoration: none;text-underline:none'>Enquist</span></a></span></i><i><span lang=EN-US style='mso-ansi-language:EN-US;mso-no-proof:yes'>, L. W. (2009). Virology in the 21st Century. </span></i><i><span lang=ES-TRAD style='mso-ansi-language: ES-TRAD;mso-no-proof:yes'>En Artculo cientfico de Rev. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681991/"><span style='color:windowtext;text-decoration:none;text-underline:none'>J Virol</span></a>, 83(11). (pg. 5296 5308).<o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>International Committe on Taxonomy of Viruses (ICTV). 2018. Information. En lnea, (pg. 5-13). </span></i><i><span lang=EN-US style='mso-ansi-language:EN-US; mso-no-proof:yes'>Recuperado de: </span></i><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'><a href="https://talk.ictvonline.org/information/"><span lang=EN-US style='color:windowtext;mso-ansi-language:EN-US;text-decoration:none; text-underline:none'>https://talk.ictvonline.org/information/</span></a></span></i><i><span lang=EN-US style='mso-ansi-language:EN-US;mso-no-proof:yes'><o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=EN-US style='mso-ansi-language:EN-US;mso-no-proof:yes'>Le, K., (1986). W. M. Stanley's crystallization of the tobacco mosaic virus, 1930-1940. </span></i><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>En Artculo cientfico de Rev. <a href="https://www.ncbi.nlm.nih.gov/pubmed/3533840" title="Isis; an international review devoted to the history of science and its cultural influences."><span style='color:windowtext;text-decoration:none;text-underline:none'>Isis</span></a>, 77(288). (pg. 450-472).<o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>Leonard, N. J., Cruickshank, K. A., Groziak, M. P., Clauson, G., L., Devadas, B. (1986). Relatives of&nbsp;Watson-Crick&nbsp;DNA, RNA cross sections. En Artculo cientfico de Rev. <a href="https://www.ncbi.nlm.nih.gov/pubmed/2425693" title="Annals of the New York Academy of Sciences."><span style='color:windowtext; text-decoration:none;text-underline:none'>Ann N&nbsp;Y&nbsp;Acad Sci,</span></a> 471(1). (pg. 255-265).<o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>Lpez, F. 1963. Concepto y Clasificacin de los Virus. En Artculo cientfico de Rev. Salud Pbl. Mex. 5(6). </span></i><i><span lang=EN-US style='mso-ansi-language: EN-US;mso-no-proof:yes'>(pg. 945-951).<o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=EN-US style='mso-ansi-language:EN-US;mso-no-proof:yes'>MacLachlan, J., &amp; Dubovi, E. 2016. Fenners Veterinary Virology. Fourth Edition. </span></i><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>In book of Virology. (pg 59). EEUU: ELSEVIER<o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>Organizacin Mundial de la Salud (OMS). 2018. Enfermedad por el virus Ebola. En lnea (pg 1-3). Recuperado de: <a href="https://www.who.int/es/news-room/fact-sheets/detail/ebola-virus-disease"><span style='color:windowtext;text-decoration:none;text-underline:none'>https://www.who.int/es/news-room/fact-sheets/detail/ebola-virus-disease</span></a> <o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>Procop, G. 2017. Koneman: diagnstico microbiolgico: texto y atlas. Septima edicin. En libro de Microbiologa. (pg. 1951-1956). Madrid-Espaa: WOLTERS KLUWER.<o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=EN-US style='mso-ansi-language:EN-US;mso-no-proof:yes'>R&amp;D Systems. (2018). Significant Events in the History of Virology. </span></i><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>En lnea. (pg. 1-3). Recuperado de: www.rndsystems.com/resources/posters/significant-events-history-virology<o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>Shors, T. 2010. Virus: Estudio molecular con orientacin clnica. Primera edicin. En libro de Virologa. (pg. 1-622). Buenos Aires-Argentina: PANAMERICANA.<o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=EN-US style='mso-ansi-language:EN-US;mso-no-proof:yes'>Theiler, M.,&nbsp;</span></i><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'><a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Smith%20HH%5BAuthor%5D&amp;cauthor=true&amp;cauthor_uid=19870634"><span lang=EN-US style='color:windowtext;mso-ansi-language:EN-US;text-decoration: none;text-underline:none'>&amp; Smith, H</span></a></span></i><i><span lang=EN-US style='mso-ansi-language:EN-US;mso-no-proof:yes'>. (1937). The use of Yellow Fever virus modified by in vitro cultivation for human immunization. </span></i><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof: yes'>En Artculo cientfico de Rev. <a href="https://www.ncbi.nlm.nih.gov/pubmed/19870634" title="The Journal of experimental medicine."><span style='color:windowtext; text-decoration:none;text-underline:none'>J Exp Med.</span></a>, 65(6). (pg. 787-800).<o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><i><span lang=EN-US style='mso-ansi-language:EN-US;mso-no-proof:yes'>Wagner, E., Martnez, H., Bloom, D., Camerini, D. (2011). </span></i><i><span lang=ES-TRAD style='mso-ansi-language:ES-TRAD;mso-no-proof:yes'>Basic Virology. Tercera edicin. En Libro de Virologa. (pg. 1-533): Blackwell Publishing.<o:p></o:p></span></i></p> <p class=MsoBibliography style='margin-left:36.0pt;text-indent:-36.0pt'><span lang=ES><o:p>&nbsp;</o:p></span></p> <p class=MsoNormal style='line-height:normal'><span lang=ES><o:p>&nbsp;</o:p></span></p> </w:Sdt> <p class=MsoNormal style='margin-top:0cm;margin-right:0cm;margin-bottom:0cm; margin-left:35.45pt;margin-bottom:.0001pt;text-indent:-35.45pt'><span lang=ES style='mso-no-proof:yes'><o:p>&nbsp;</o:p></span></p> </div> <div style='mso-element:footnote-list'><![if !supportFootnotes]><br clear=all> <hr align=left size=1 width="33%"> <![endif]> <div style='mso-element:footnote' id=ftn1> <p class=MsoNormal style='margin-bottom:0cm;margin-bottom:.0001pt;text-align: justify;line-height:normal;mso-layout-grid-align:none;text-autospace:none'><a style='mso-footnote-id:ftn1' href="#_ftnref1" name="_ftn1" title=""><span class=MsoFootnoteReference><span lang=ES style='font-size:9.0pt;mso-bidi-font-family: Calibri;mso-bidi-theme-font:minor-latin'><span style='mso-special-character: footnote'><![if !supportFootnotes]><span class=MsoFootnoteReference><span lang=ES style='font-size:9.0pt;line-height:105%;font-family:"Calibri",sans-serif; mso-ascii-theme-font:minor-latin;mso-fareast-font-family:Calibri;mso-fareast-theme-font: minor-latin;mso-hansi-theme-font:minor-latin;mso-bidi-theme-font:minor-latin; mso-ansi-language:ES;mso-fareast-language:EN-US;mso-bidi-language:AR-SA'>[1]</span></span><![endif]></span></span></span></a><span lang=ES style='font-size:9.0pt;mso-bidi-font-family:Calibri;mso-bidi-theme-font: minor-latin'> </span><span lang=ES style='font-size:9.0pt;mso-fareast-font-family: Arial;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin'>Artculo original derivado del proyecto de investigacin FCI de la Universidad de Guayaquil, titulado:  </span><span class=SpellE><span lang=ES style='font-size: 9.0pt;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;color:black'>Ecoepidemiologa</span></span><span lang=ES style='font-size:9.0pt;mso-bidi-font-family:Calibri;mso-bidi-theme-font: minor-latin;color:black'> del Virus de Encefalitis Equina del Este, en 2 sectores de las zonas 5 y 8 de las provincias del Guayas y los Ros, repblica del Ecuador </span><span lang=ES style='font-size:9.0pt;mso-fareast-font-family: Arial;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin'>- Entidad financiadora: Universidad de Guayaquil, fecha de realizacin entre <span class=GramE>Enero</span> a Junio del 2019</span><span lang=ES style='font-size: 9.0pt;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin'><o:p></o:p></span></p> <p class=MsoFootnoteText style='text-align:justify'><span class=MsoFootnoteReference><span style='font-size:9.0pt;font-family:"Calibri",sans-serif; mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;mso-bidi-theme-font: minor-latin;mso-ansi-language:ES-EC'>2</span></span><span style='font-size: 9.0pt;font-family:"Calibri",sans-serif;mso-ascii-theme-font:minor-latin; mso-hansi-theme-font:minor-latin;mso-bidi-theme-font:minor-latin;mso-ansi-language: ES-EC'> </span><span style='font-size:9.0pt;font-family:"Calibri",sans-serif; mso-ascii-theme-font:minor-latin;mso-fareast-font-family:Arial;mso-hansi-theme-font: minor-latin;mso-bidi-theme-font:minor-latin;mso-ansi-language:ES-EC'>Mdico Veterinario y Zootecnista, Magster en Microbiologa con mencin Biomdica, Coordinador de Investigacin de la FMVZ de la Universidad de Guayaquil, roberto.coellope@ug.edu.ec, </span><span style='font-size:9.0pt;font-family:"Calibri",sans-serif; mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;mso-bidi-theme-font: minor-latin;mso-ansi-language:ES-EC'>https://orcid.org/</span><span lang=EN-US style='font-size:9.0pt;font-family:"Calibri",sans-serif;mso-ascii-theme-font: minor-latin;mso-hansi-theme-font:minor-latin;mso-bidi-theme-font:minor-latin'><a href="http://orcid.org/0000-0001-5152-2843"><span lang=ES-TRAD style='color:windowtext;mso-ansi-language:ES-EC'><span lang=ES-TRAD>0000-0001-5152-2843</span></span></a></span><span style='font-size:9.0pt;font-family:"Calibri",sans-serif;mso-ascii-theme-font: minor-latin;mso-hansi-theme-font:minor-latin;mso-bidi-theme-font:minor-latin; mso-ansi-language:ES-EC'>, ID: 60072042</span><span style='font-family:"Arial Narrow",sans-serif; mso-fareast-font-family:Arial;mso-bidi-font-family:Arial;mso-ansi-language: ES-EC'><o:p></o:p></span></p> </div> </div> </body> </html>

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.